In Brief:
We investigated whether initial conservative treatment interventions for osteoporotic vertebral fracture (OVF) influence patient outcomes, including Short Form-36 (SF-36) physical component summary 40 or less, SF-36 mental component summary 40 or less, reduced activities of daily living, prolonged back pain, cognitive impairment, and vertebral collapse. The treatment intervention factors did not affect the patient outcomes 6 months after OVF. Middle-column injury was a significant risk factor for both clinical and radiological outcomes.