In Brief:
This systematic review evaluated patient outcomes from four treatment groups: ACDF with allograft (allograft, n = 1341), ACDF with autograft (autograft, n = 568), ACDF with cage (cage, n = 87), and cervical disc arthroplasty (arthroplasty, n = 603). These treatments provided similar improvements in pain, function, and quality of life with low adverse event rates. High fusion rates were achieved with all ACDF procedures.