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Moving Forward From rhBMP-2: Open Science and Data Sharing

Low, Jeffrey B. AB*; Ross, Joseph S. MD, MHS; Krumholz, Harlan M. MD, SM

doi: 10.1097/BRS.0000000000000256
Editorial

*Yale University School of Medicine, New Haven, CT;

Section of General Internal Medicine and the Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine; and the Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT; and

Section of Cardiovascular Medicine and the Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine; Department of Health Policy and Management, Yale School of Public Health; and Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.

Address correspondence and reprint requests to Harlan M. Krumholz, MD, SM, Department of Internal Medicine/Section of Cardiovascular Medicine, Yale University School of Medicine, 1 Church St., Ste 200, New Haven, CT 06510; E-mail: harlan.krumholz@yale.edu

Acknowledgment date: January 7, 2014. Acceptance date: January 9, 2014.

The device(s)/drug(s) is/are FDA-approved or approved by corresponding national agency for this indication.

The manuscript includes unlabeled/investigational uses of the products/devices listed below and the status of these is disclosed in the manuscript: we briefly summarize the findings from 2 systematic reviews of rhBMP-2, including both approved uses and unapproved uses.

The National Heart, Lung, and Blood Institute (Center for Cardiovascular Outcomes Research at Yale University) fund (grant 1 U01 HL105270-04) was received to support the work of Dr. Krumholz.

The National Institute on Aging and the American Federation for Aging Research through the Paul B. Beeson Career Development Award Program fund (grant K08 AG032886) was received to support the work of Dr. Ross.

Relevant financial activities outside the submitted work: grant, stock/stock options, grants/grants pending, endowed scholarship, and board membership.

© 2014 by Lippincott Williams & Wilkins