Retrospective cohort study.
To investigate the impact of prolonged opioid use
in the preoperative treatment plan of degenerative lumbar stenosis (DLS).
Summary of Background Data.
Patients undergoing operative treatment for DLS with concomitant opioid use
represent a clinically challenging population. The relative paucity of data on the relationship between preoperative opioid use
and clinical outcomes
in the workers’ compensation
(WC) population necessitates further study of this unique population.
We identified 140 Ohio WC patients who underwent lumbar decompression
and had received preoperative opioid prescriptions between 1993 and 2013. Our study cohorts were formed based on opioid use
duration, which included short-term use (<3 months) and long-term use (>3 months). Our primary outcome was if patients were able to make a stable return to work
(RTW). A multivariate regression analysis was used to determine the impact of the duration of preoperative opioid use
on return to work
rates. We also compared many secondary outcomes after surgery between both groups.
Patients on opioids less than 3 months had a significantly higher RTW rate compared with those who used opioids longer than 3 months [25/60 (42%) vs.
18/80 (23%); P
= 0.01]. A logistic regression was performed to examine the effect of preoperative opioid therapy duration on RTW status. Our regression model showed that opioid use
greater than 3 months remained a significant negative predictor of RTW (OR: 0.35, 95% CI: 0.13–0.89; P
= 0.02). Patients who remained on opioid therapy longer than 3 months cost the Ohio Bureau of Workers’ Compensation
$70,979 more than patients who were on opioid therapy for less than 3 months (P
Prolonged preoperative opioid use
was associated with poor clinical outcomes
after lumbar decompression
. These results suggest that a shorter course of opioid therapy and earlier surgical intervention may improve outcomes and lower postoperative morbidity in patients with DLS.
Level of Evidence: 3