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An Effective Treatment Option for Kümmell Disease With Neurological Deficits

Modified Transpedicular Subtraction and Disc Osteotomy Combined With Long-Segment Fixation

Zhang, Xuesong MD; Hu, Wenhao MD; Yu, Jiayi MD; Wang, Zheng MD; Wang, Yan PhD

doi: 10.1097/BRS.0000000000001467

Study Design. Retrospective cohort study.

Objective. To illustrate the technique of modified transpedicular subtraction and disc osteotomy combined with long-segment fixation for the treatment of Kümmell disease with neurologic deficits and to evaluate clinical and radiographic results of patients treated with the technique.

Summary of Background Data. Kümmell disease is a clinical condition in which patients develop a kyphosis in the lower thoracolumbar spinal region months to years after sustaining an otherwise asymptomatic minor spinal. Currently, for patients with neurological deficits, anterior decompression with bone grafting fusion, posterior decompression with pedicle subtraction osteotomy, or a combined anterior and posterior approach operation were used; however, there is no standard treatment and no single effective treatment for Kümmell disease.

Methods. Between May 2009 and May 2012, we reviewed 12 patients experiencing Kümmell disease with neurological deficits who underwent modified transpedicular subtraction and disc osteotomy combined with long-segment fixation. Preoperative and postoperative Cobb angle, visual analog scale, Asia Spinal Injury Association, and sagittal balance were documented. The patients were followed up for 33 months on average.

Results. The Cobb angles decreased from 43.33 ± 7.44° to 1.92 ± 2.74° (P < 0.01), the mean visual analog scale reduced from 7.17 ± 1.27° to 1.17 ± 1.03° (P < 0.01), and the sagittal vertical angle improved from 14.82 ± 3.56 cm to 5.15 ± 2.10 cm (P < 0.01). Kyphotic deformity was successfully corrected and solid fusion was achieved in all cases. Neurologic function of nine cases was improved to various degrees.

Conclusion. Modified transpedicular subtraction and disc osteotomy combined with long-segment fixation is an effective treatment option for Kümmell disease with neurological deficits.

Level of Evidence: 4

Department of Orthopaedics, Chinese PLA General Hospital

Department of Renal Cancer and Melanoma, Peking University Cancer Hospital, Beijing, China.

Address correspondence and reprint requests to Yan Wang, PhD; E-mail:

Received 1 September, 2015

Revised 2 November, 2015

Accepted 15 December, 2015

XZ and WH contributed equally to this work.

The manuscript submitted does not contain information about medical device(s)/drug(s).

No funds were received in support of this work.

No relevant financial activities outside the submitted work.

Copyright © 2016 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.