A case report.
To illustrate a rare case of oncogenous osteomalacia
caused by a spinal thoracic myopericytoma
Summary of Background Data. Osteomalacia
related to a tumor is well known. The cause of the disorder is usually a highly vascularized, benign tumor of mesenchymal origin. Location of the tumor in the spine is very rare. Removal of the tumor is followed by resolution of osteomalacia
Diagnosis of oseomalacia was established on the presence of cardinal clinical, biologic, and radiologic features of osteomalacia
. Localization of the tumor at T5 and T6 levels was obtained by magnetic resonance imaging. Surgical treatment consisted in a circumferential correction-fusion with hemivertebrectomy of T5 and T6 and tumor removal.
Tumor removal was rapidly followed by disappearance of the clinical symptoms of osteomalacia
, and by correction of hypophosphatemia. At 2-years follow-up, no recurrence of the tumor was detectable on imaging studies—the correction fusion remained stable. Histologically, the tumor was classified as a myopericytoma
. There was no relapse of the clinical features of osteomalacia
. However, secondary recurrence of the biologic markers due to an incomplete tumor removal was disclosed.
Removal of the tumor was followed by healing of the clinical features of osteomalacia
, demonstrating the causal connection between the myopericytoma
and the osteopathy.