Prospective 6-center study.
To evaluate outcomes of cervical disc replacement
performed adjacent to a prior cervical fusion
Summary of Background Data.
The use of disc replacement adjacent to a prior anterior cervical decompression and fusion
(ACDF) is an attractive reconstructive option, obviating the need for a multilevel fusion
. This study reports outcomes from patients with and without previous ACDF receiving the porous coated motion (PCM
) artificial cervical disc in a United States Federal Drug Administration Investigational Device Exemption trials.
Patients between ages of 18 and 65 with single-level cervical radiculopathy and/or myelopathy, unresponsive to at least 6 weeks of nonsurgical therapy, or experiencing progressive neurologic symptoms were enrolled. Clinical outcomes are compared for patients receiving a PCM
disc at a level adjacent to a prior ACDF (“adjacent”) and those without having previously had fusion
patients were primary (mean age: 44.4 years.) and 26 patients had previous “adjacent level
surgery (mean age: 46.4 years). Surgery time was similar in both groups (96 minutes and 98 minutes, respectively; P
= 0.761), and mean blood loss was 76 mL and 66 mL in the 2 groups, respectively (P
= 0.491). Clinical outcomes using Neck Disability Index and Visual Analog Scores neck and arm scores showed significant improvement after surgery and were similar between groups at all time points. Revision surgery occurred in 2 of 126 primary patients, and in 2 of 26 patients in the adjacent-to-fusion
Although the level adjacent to a prior cervical fusion
is subject to increased biomechanical forces, potentially leading to a higher risk of failure, the PCM
disc was well tolerated in the short term. The early clinical results of disc replacement adjacent to a prior fusion
are good and comparable to the outcomes after primary disc replacement surgery. However, in view of the small study population and short-term follow-up, continued study is mandatory.