A retrospective matched cohort study.
To comprehensively compare the 2-year postoperative results of posterior correction and fusion with segmental pedicle screw instrumentation versus with hybrid (proximal hooks and distal pedicle screws) constructs in adolescent idiopathic scoliosis (AIS) treated at a single institution.
Despite the reports of satisfactory correction and maintenance of scoliotic curves by pedicle screw instrumentation, there have been no reports on the comprehensive comparison of AIS treatment after segmental pedicle screw instrumentation versus hybrid instrumentation.
A total of 58 AIS patients that underwent posterior fusion with hybrid instrumentation (29) or pedicle screw (29) instrumentation at a single institution were sorted and matched according to four criteria: similar patient age, fusion levels, identical Lenke curve type, and identical operative methods. Patients were compared at 2-year follow-up according to radiographic changes, operative time, intraoperative blood loss, pulmonary function tests, and SRS-24 outcome scores.
The two cohorts were well matched. The preoperative major Cobb angle averaged 62° in the screw group and 60° in the hybrid group. Average major curve correction was 70% in the screw group and 56% in the hybrid group (P = 0.001). At 2-year follow-up, major curve correction was 65% and 46%, respectively (P < 0.001). At 2-year follow-up, thoracic sagittal Cobb angle changes between T5 and T12 were 9.0° decrease in the screw group and 2.4° decrease in the hybrid group compared with preoperative (P = 0.024). There were no differences in the lowest instrumented vertebra below the lower end vertebra (P = 0.56), operative time (P = 0.14), and average estimated blood loss (P = 0.54). Two years following surgery, the screw group demonstrated improved percent predicted pulmonary function values compared with that of the hybrid group (FVC; 81% → 81% in screw group vs. 85% → 79% in hybrid group P = 0.08, FEV1; 73% → 79% in screw group vs. 79% → 75% in hybrid group, P = 0.006). Postoperative total SRS-24 scores were similar in both groups (hybrid group: 99 vs. screw group: 95) (P = 0.19). There were no neurologic complications related to hybrid or pedicle screw instrumentation.
Pedicle screw instrumentation offers a significantly better major curve correction and postoperative pulmonary function values without neurologic problems compared with hybrid constructs. Both instrumentation methods offer similar junctional change, lowest instrumented vertebra, operative time, and postoperative SRS-24 outcome scores in the operative treatment of AIS.
This comparison study of 58 adolescent idiopathic scoliosis patients that underwent posterior fusion with exclusive pedicle screw (n = 29) or hybrid (proximal hooks and distal pedicle screws, n = 29) instrumentation were sorted and matched according to four criteria: age, curve type, fusion level, and operative method. Segmental pedicle screw instrumentation offered and maintained a significantly better coronal curve correction without neurologic problems and improved pulmonary function values in the operative treatment of adolescent idiopathic scoliosis.
From the Department of Orthopaedic Surgery, Washington University School of Medicine, and Shriners Hospitals for Children, St. Louis, MO.
Acknowledgment date: June 27, 2005. Acceptance date: August 9, 2005.
The device(s)/drug(s) that is/are the subject of this manuscript is/are FDA-approved or approved by corresponding national agency for this indication.
No funds were received in support of this work. One or more of the author(s) has/have received or will receive benefits for personal or professional use from a commercial party related directly or indirectly to the subject of this manuscript: e.g., honoraria, gifts, consultancies, royalties, stocks, stock options, decision making position.
Address correspondence and reprint requests to Lawrence G. Lenke, MD, Department of Orthopaedic Surgery, 11300 West Pavilion, One Barnes Jewish Plaza, St. Louis, MO 63110; E-mail: email@example.com