A Comprehensive Study of Physical Parameters, Biomechanical Properties, and Statistical Correlations of Iliac Crest Bone Wedges Used in Spinal Fusion Surgery: IV. Effect of Gamma Irradiation on Mechanical and Material PropertiesZhang, Yongxing, PhD*; Homsi, Diana*; Gates, Kevin*; Oakes, Kevin*; Sutherland, Vicki*; Wolfinbarger, Lioyd Jr, PhD*,†Spine: February 1994 - Volume 19 - Issue 3 - p 304–308 Bone Graft-Physical, Mechanical, Material Properties: PDF Only Buy Abstract Author InformationAuthors The effects of gamma irradiation on mechanical and material properties of iliac crest wedges used in spinal fusion surgery were studied using uniaxial compresion testing. The irradiated iliac crest wedges were exposed to 2–2.5 mrad as fresh-frozen and freeze-dried tissues. There were no significant differences in mechanical or material properties of the iliac crest wedges exposed to dosages of 2–2.5 mrad when compared to the nonirradiated wedges. It is suggested that 2–2.5 mrad is an acceptable dose for gamma irradiation sterilization of iliac crest wedges used in spinal fusion surgery and that these tissues may be treated at either the preprocessing or postprocessing stage of wedge production. *Center for Biotechnology, Old Dominion University, Norfolk, †LifeNet Transplant Services, 5809 Ward Court, Virginia Beach, Virginia. © Lippincott-Raven Publishers.