Original Article: PDF OnlyEpidural Lipomatosis in Steroid-Treated PatientsFESSLER, RICHARD G. MD, PhD*; JOHNSON, DOUGLAS L. MD, PhD†; BROWN, FREDERICK D. MD†; ERICKSON, ROBERT K. MD†; REID, STEVEN A. MD*; KRANZLER, LEONARD MD† Author Information *From the Department of Neurological Surgery, University of Florida, College of Medicine, Gainesville, Florida †From the Section of Neurosurgery, University of Chicago Medical Center, Chicago, Illinois Spine: February 1992 - Volume 17 - Issue 2 - p 183-188 Buy Abstract Epidural lipomatosis is a condition in which excess adipose tissue is deposited circumferentially about the spinal cord in the epidural space. It is most frequently seen in patients on chronic steroid treatment for a variety of medical problems and can present as nonspecific back pain, radiculopathy, or frank spinal cord compression. Diagnosis and treatment have generally relied on multilevel decompressive laminectomy after myelography and computed tomography. The immunocompromised state and the reported postoperative mortality (22%) of these patients, however, suggests that nonoperative therapy may be preferable whenever possible. Five cases of epidural lipomatosis are reported, and previous literature is reviewed for presentation, evaluation, and treatment of this condition. © Lippincott-Raven Publishers.