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doi: 10.1097/01.shk.0000457206.30192.87
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SHOCK®

Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches

OFFICIAL JOURNAL OF THE SHOCK SOCIETY, THE EUROPEAN SHOCK SOCIETY, THE INDONESIAN SHOCK SOCIETY, THE INTERNATIONAL FEDERATION OF SHOCK SOCIETIES, AND THE OFFICIAL AND INTERNATIONAL JOURNAL OF THE JAPAN SHOCK SOCIETY

Volume 42, No. 1 July 2014

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Commentary

Mark G. Clemens 1 What’s New in Shock, July 2014

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Review Article

Ulrike Niesler, Annette Palmer, Peter Radermacher, and Markus S. Huber-Lang 3 Role of Alveolar Macrophages in the Inflammatory Response After Trauma

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Clinical Aspects

Kai-Chao Yang, Min-Jie Zhou, Jason L. Sperry, Liu Rong, Xiao-Guang Zhu, Lei Geng, Wei Wu, Gang Zhao, Timothy R. Billiar, and Qi-Ming Feng 11 Significant Sex-Based Outcome Differences in Severely Injured Chinese Trauma Patients

Josiane Festti, Cintia Magalhães Carvalho Grion, Luciana Festti, Tânia Longo Mazzuco, Helena Pantelion Lima-Valassi, Vinícius Nahime Brito, Décio Sabbatini Barbosa, and Alexandre José Faria Carrilho 16 Adrenocorticotropic Hormone but not High-density Lipoprotein Cholesterol or Salivary Cortisol was a Predictor of Adrenal Insufficiency in Patients with Septic Shock

Batric Popovic, Renaud Fay, Aurelie Cravoisy-Popovic, and Bruno Levy 22 Cardiac Power Index, Mean Arterial Pressure, and Simplified Acute Physiology Score II Are Strong Predictors of Survival and Response to Revascularization in Cardiogenic Shock

SDC Supplemental Digital Content is available in the text.

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Basic Science Aspects

Maria del Pilar Huby, Jessica C. Cardenas, Lisa A. Baer, Nick S. Pawelczyk, John R. Salsbury, Yao-Wei W. Wang, Nena Matijevic, John B. Holcomb, and Charles E. Wade 27 Establishment of Methods for Performing Thrombelastography and Calibrated Automated Thrombography in Rats

Xia Zhang, Chen Lu, Ming Gao, Xinyun Cao, Tuanzhu Ha, John H. Kalbfleisch, David L. Williams, Chuanfu Li, and Race L. Kao 31 Toll-Like Receptor 4 Plays a Central Role in Cardiac Dysfunction During Trauma Hemorrhage Shock

Slava M. Belenkiy, John S. Berry, Andriy I. Batchinsky, Chonna Kendrick, Corina Necsoiu, Bryan S. Jordan, José Salinas, and Leopoldo C. Cancio 38 The Noninvasive Carbon Dioxide Gradient (NICO2G) During Hemorrhagic Shock

Babs Soller, Charles Smith, Fengmei Zou, Gwenn E.C. Ellerby, M. Dale Prince, and Jill L. Sondeen 44 Investigation of Noninvasive Muscle pH and Oxygen Saturation During Uncontrolled Hemorrhage and Resuscitation in Swine

SDC Supplemental Digital Content is available in the text.

Diego F. Niño, David M. Cauvi, and Antonio De Maio 52 Itraconazole, a Commonly Used Antifungal, Inhibits Fcγ Receptor–Mediated Phagocytosis: Alteration of Fcγ Receptor Glycosylation and Gene Expression

SDC Supplemental Digital Content is available in the text.

Maria Theresa Kuipers, Geartsje Jongsma, Maria A. Hegeman, Anita M. Tuip-de Boer, Esther K. Wolthuis, Goda Choi, Paul Bresser, Tom van der Poll, Marcus J. Schultz, and Catharina W. Wieland 60 TLR2 Deficiency Aggravates Lung Injury Caused by Mechanical Ventilation

Min Xu, Changjun Tan, Jinwu Hu, Salamah Mohammad Alwahsh, Jun Yan, Jie Hu, Zhi Dai, Zheng Wang, Jian Zhou, Jia Fan, and Xiaowu Huang 65 Expression of Hemopexin in Acute Rejection of Rat Liver Allograft Identified by Serum Proteomic Analysis

Jing Jiao, Min Gao, Huali Zhang, Nian Wang, Zihui Xiao, Ke Liu, Mingshi Yang, Kangkai Wang, and Xianzhong Xiao 75 Identification of Potential Biomarkers by Serum Proteomics Analysis in Rats with Sepsis

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Commentary

Peter Chen and Marc G. Jeschke 83 What’s New in Shock, August 2014?

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Clinical Aspects

Manuela Avolio, Paola Diamante, Maria Luisa Modolo, Rita De Rosa, Paola Stano, and Alessandro Camporese 86 Direct Molecular Detection of Pathogens in Blood as Specific Rule-In Diagnostic Biomarker in Patients with Presumed Sepsis: Our Experience on a Heterogeneous Cohort of Patients with Signs of Infective Systemic Inflammatory Response Syndrome

Roy Nadler, Victor A. Convertino, Sami Gendler, Gadi Lending, Ari M. Lipsky, Sylvain Cardin, Alexander Lowenthal, and Elon Glassberg 93 The Value of Noninvasive Measurement of the Compensatory Reserve Index in Monitoring and Triage of Patients Experiencing Minimal Blood Loss

Adit A. Ginde, Patrick J. Blatchford, Stephen Trzeciak, Judd E. Hollander, Robert Birkhahn, Ronny Otero, Tiffany M. Osborn, Eugene Moretti, H. Bryant Nguyen, Kyle J. Gunnerson, David Milzman, David F. Gaieski, Munish Goyal, Charles B. Cairns, Emanuel P. Rivers, and Nathan I. Shapiro 99 Age-Related Differences in Biomarkers of Acute Inflammation During Hospitalization for Sepsis

SDC Supplemental Digital Content is available in the text.

Nehemiah T. Liu, John B. Holcomb, Charles E. Wade, Mark I. Darrah, and Jose Salinas 108 Utility of Vital Signs, Heart Rate Variability and Complexity, and Machine Learning for Identifying the Need for Lifesaving Interventions in Trauma Patients

Kathryn M. Gores, Angela S. Delsing, Sara J. Kraus, Linda Powers, Daniel A. Vaena, Mohammed M. Milhem, Martha Monick, and Kevin C. Doerschug 115 Plasma Angiopoietin 2 Concentrations Are Related to Impaired Lung Function and Organ Failure in a Clinical Cohort Receiving High-Dose Interleukin 2 Therapy

Rianne M. Jongman, Jan G. Zijlstra, Wendelinde F. Kok, Annemarie E. van Harten, Massimo A. Mariani, Jill Moser, Michel M. R. F. Struys, Anthony R. Absalom, Grietje Molema, Thomas W. L. Scheeren, and Matijs van Meurs 121 Off-Pump Cabg Surgery Reduces Systemic Inflammation Compared with On-Pump Surgery but Does Not Change Systemic Endothelial Responses: A Prospective Randomized Study

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Short Communication

Katharina Biller, Peter Fae, Reinhard Germann, Heinz Drexel, Autar K. Walli, and Peter Fraunberger 129 Cholesterol Rather Than Procalcitonin or C-Reactive Protein Predicts Mortality in Patients with Infection

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Basic Science Aspects

Meenakshi Rani, Qiong Zhang, and Martin G. Schwacha 133 Gamma Delta T-Cells Regulate Wound Myeloid Cell Activity After Burn

Yuka Sumi, Tobias Woehrle, Yu Chen, Yi Bao, Xiaoou Li, Yongli Yao, Yoshiaki Inoue, Hiroshi Tanaka, and Wolfgang G. Junger 142 Plasma ATP is Required for Neutrophil Activation in a Mouse Sepsis Model

Raquel Rodríguez-González, José LuisMartín-Barrasa, Ángela Ramos-Nuez, Ana María Cañas-Pedrosa, María Teresa Martínez-Saavedra, Miguel Ángel García-Bello, Josefina López-Aguilar, Aurora Baluja, Julián Álvarez, Arthur S. Slutsky, and Jesús Villar 148 Multiple System Organ Response Induced by Hyperoxia in a Clinically Relevant Animal Model of Sepsis

SDC Supplemental Digital Content is available in the text.

Mustafa Kassim, Marzida Mansor, Tengku Ain Kamalden, Ina Ismiarti Shariffuddin, Mohd Shahnaz Hasan, Gracie Ong, Shamala Devi Sekaran, Anwar Suhaimi, Nazeh Al-Abd, and Kamaruddin Mohd Yusoff 154 Caffeic Acid Phenethyl Ester (CAPE): Scavenger of Peroxynitrite In Vitro and in Sepsis Models

Hui Liang, Xue-Min Song, Xiao-Jing Wu, Jian-Guo Li, Yi Han, Yan-Lin Wang, Hui Li, Zong-Ze Zhang, Lin-Li Le, and Yang Xu 161 Muramyl Dipeptide Enhances Thermal Injury–Induced Inflammatory Cytokine Production and Organ Function Injury in Rats

Suely Kubo Ariga, Fátima Bernardes Abatepaulo, Edielle Sant Anna Melo, Irineu Tadeu Velasco, Fabiano Pinheiro da Silva, Thais Martins de Lima, and Francisco Garcia Soriano 168 Endotoxin Tolerance Drives Neutrophil To Infectious Site

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Editorial Comment

Jan P. Roesner and Christoph Thiemermann 174 Mirror, Mirror on the Wall, is Off-Pump Better Than On-Pump at All?

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Commentary

Anirban Banerjee 177 What’s New in Shock? September 2014

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Review Article

Milica Bajčetić, Snežana Spasić, and Ivan Spasojević 179 Redox Therapy in Neonatal Sepsis: Reasons, Targets, Strategy, and Agents

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Clinical Aspects

Stephen W. Davies, Jimmy T. Efird, Christopher A. Guidry, Tjasa Hranjec, Rosemarie Metzger, Brian R. Swenson, and Robert G. Sawyer 185 Does it Matter if We Get it Right? Impact of Appropriateness of Empiric Antimicrobial Therapy Among Surgical Patients

Arnaud Gacouin, Mikael Roussel, Jerome Le Priol, Imane Azzaoui, Fabrice Uhel, Thierry Fest, Yves Le Tulzo, and Jean Marc Tadie 192 Acute Alcohol Exposure has an Independent Impact on C-Reactive Protein Levels, Neutrophil CD64 Expression, and Subsets of Circulating White Blood Cells Differentiated by Flow Cytometry in Nontrauma Patients

Afshin Parsikia, Kathleen Bones, Mark Kaplan, Jay Strain, Pak Shan Leung, Jorge Ortiz, and Amit R. T. Joshi 199 The Predictive Value of Initial Serum Lactate in Trauma Patients

Sung Yeon Hwang, Tae Gun Shin, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Tae Rim Lee, Won Chul Cha, Min Seob Sim, Keun Jeong Song, and Yeon Kwon Jeong 205 Association Between Hemodynamic Presentation and Outcome in Sepsis Patients

Ninad B. Gawande, Nilesh Keshav Tumram, and Anand Paikuji Dongre 211 Cardiac Changes in Hospitalized Patients of Trauma

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Basic Science Aspects

Yong Zhang, Jinxiang Zhang, Sebastian Korff, Faez Ayoob, Yoram Vodovotz, and Timothy R. Billiar 218 Delayed Neutralization of Interleukin 6 Reduces Organ Injury, Selectively Suppresses Inflammatory Mediator, and Partially Normalizes Immune Dysfunction Following Trauma and Hemorrhagic Shock

Xianwen Hu, Zhengfei Yang, Min Yang, Jie Qian, Jena Cahoon, Jiefeng Xu, Shijie Sun, and Wanchun Tang 228 Remote Ischemic Preconditioning Mitigates Myocardial and Neurological Dysfunction via KATP Channel Activation in a Rat Model of Hemorrhagic Shock

Timo Brandenburger, Hilbert Grievink, Nicole Heinen, Franziska Barthel, Ragnar Huhn, Friederike Stachuletz, Malte Kohns, Benedikt Pannen, and Inge Bauer 234 Effects of Remote Ischemic Preconditioning and Myocardial Ischemia on MicroRNA-1 Expression in the Rat Heart In Vivo

Tao Li, Yu Zhu, Jia-tao Zang, Xiao-yong Peng, Dan Lan, Guang-ming Yang, Jing Xu, and Liang-ming Liu 239 Rho Kinase Acts as a Downstream Molecule to Participate in Protein Kinase C€ Regulation of Vascular Reactivity After Hemorrhagic Shock in Rats

David M. Cauvi, Michael R. Williams, Jose A. Bermudez, Gabrielle Armijo, and Antonio De Maio 246 Elevated Expression of IL-23/IL-17 Pathway–Related Mediators Correlates with Exacerbation of Pulmonary Inflammation During Polymicrobial Sepsis

Andaleb Kholmukhamedov, Christoph Czerny, Jiangting Hu, Justin Schwartz, Zhi Zhong, and John J. Lemasters 256 Minocycline And Doxycycline, But Not Tetracycline, Mitigate Liver and Kidney Injury After Hemorrhagic Shock/Resuscitation

Jordan E. Fishman, Gal Levy, Vamsi Alli, Xiaozhong Zheng, Damian J. Mole, and Edwin A. Deitch 264 The Intestinal Mucus Layer is a Critical Component of the Gut Barrier that is Damaged During Acute Pancreatitis

Hong Jiang, Rong Hu, Lulu Sun, Dongdong Chai, Zhendong Cao, and Qifang Li 271 Critical Role of Toll-Like Receptor 4 in Hypoxia-Inducible Factor 1α Activation During Trauma/Hemorrhagic Shock–Induced Acute Lung Injury After Lymph Infusion in Mice

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Letters to the Editor

Kwok M. Ho and Benjamin Silbert 279 Impact of Arterial Oxygen Tension on Venous Oxygen Saturation

Matthieu Legrand, and Fabrice ValléeReply to the Letter to the Editor: “Impact of Arterial Oxygen Tension on Venous Oxygen Saturation”

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Erratum

281 Effects of a Novel Anticoagulant Compound (TV7130) in an Ovine Model of Septic Shock: Erratum

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Commentary

Lyle L. Moldawer 283 What’s New in Shock, October 2014?

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Review Articles

Gabriela Camicia, Roberto Pozner, and Gabriela de Larrañaga 286 Neutrophil Extracellular Traps in Sepsis

Jennifer D. Paratz, Kellie Stockton, Elizabeth D. Paratz, Stijn Blot, Michael Muller, Jeffrey Lipman, and Robert J. Boots 295 Burn Resuscitation—Hourly Urine Output Versus Alternative Endpoints: A Systematic Review

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Clinical Aspects

Biswadev Mitra, Belinda J. Gabbe, Kirsi-Maija Kaukonen, Alexander Olaussen, David J. Cooper, and Peter A. Cameron 307 Long-Term Outcomes of Patients Receiving a Massive Transfusion After Trauma

Jennifer A. Muszynski, Ryan Nofziger, Kristin Greathouse, Jyotsna Nateri, Lisa Hanson-Huber, Lisa Steele, Kathleen Nicol, Jonathan I. Groner, Gail E. Besner, Corey Raffel, Susan Geyer, Osama El-Assal, and Mark W. Hall 313 Innate Immune Function Predicts the Development of Nosocomial Infection in Critically Injured Children

Asako Matsushima, Hiroshi Ogura, Taichin Koh, Takeshi Shimazu, and Hisashi Sugimoto 322 Enhanced Expression of Aquaporin 9 in Activated Polymorphonuclear Leukocytes in Patients with Systemic Inflammatory Response Syndrome

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Basic Science Aspects

Ruoyu Hu, Yan Cheng, Hua Jing, and Haiwei Wu 327 Erythropoietin Promotes the Protective Properties of Transplanted Endothelial Progenitor Cells Against Acute Lung Injury via PI3K/Akt Pathway

SDC Supplemental Digital Content is available in the text.

Juan Rodolfo Mella, Evan L. Chiswick, Elizabeth King, and Daniel G. Remick 337 Location, Location, Location: Cytokine Concentrations are Dependent on Blood Sampling Site

Yongzhi Wang, Oscar Ö. Braun, Su Zhang, Lingtao Luo, Eva Norström, and Henrik Thorlacius 343 Dynamic Changes in Thrombin Generation in Abdominal Sepsis in Mice

Zi-Gang Zhao, Li-Min Zhang, Yong-Zhuang Lv, Yong-Hua Si, Chun-Yu Niu, and Ji-Cheng Li 350 Changes in Renal Tissue Proteome Induced by Mesenteric Lymph Drainage in Rats After Hemorrhagic Shock with Resuscitation

Ranran Li, Jan G. Zijlstra, Jan A.A.M. Kamps, Matijs van Meurs, and Grietje Molema 356 Abrupt Reflow Enhances Cytokine-Induced Proinflammatory Activation of Endothelial Cells During Simulated Shock and Resuscitation

SDC Supplemental Digital Content is available in the text.

Jing-gang Xia, Fei-fei Xu, Yang Qu, Dan-dan Song, Hong Shen, and Xiu-hua Liu 365 Atorvastatin Post-Conditioning Attenuates Myocardial Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress–Related Apoptosis

Jolana Cermanova, Zuzana Kadova, Eva Dolezelova, Marie Zagorova, Vaclav Safka, Milos Hroch, Tomas Laho, Magdalena Holeckova, Jaroslav Mokry, Petra Kovarikova, Jan Bures, Martin Sterba, and Stanislav Micuda 372 Deferoxamine but not Dexrazoxane Alleviates Liver Injury Induced by Endotoxemia in Rats

SDC Supplemental Digital Content is available in the text.

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Commentary

Krishnan Raghavendran 381 What’s New in Shock, November 2014?

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Clinical Aspects

Anne M. Drewry, Navdeep Samra, Lee P. Skrupky, Brian M. Fuller, Stephanie M. Compton, and Richard S. Hotchkiss 383 Persistent Lymphopenia After Diagnosis of Sepsis Predicts Mortality

Sanjeev Noel, Laura Zheng, Ana Navas-Acien, and Ralph J. Fuchs 392 The Effect of Ex Vivo CDDO-Me Activation on Nuclear Factor Erythroid 2–Related Factor 2 Pathway in White Blood Cells from Patients with Septic Shock

Yun Zhang, Shun-Liang Gao, Shao-Yang Zhang, Zhong-Yan Liang, Wen-Qiao Yu, and Ting-Bo Liang 400 Six Cases of Severe Acute Pancreatitis Complicated with Vancomycin-Resistant Enterococcus Enteritis

Sven Asmussen, Michael Salter, Donald S. Prough, George C. Kramer, Christer Svensen, Melinda Sheffield-Moore, and Michael P. Kinsky 407 Isoproternenol Increases Vascular Volume Expansion and Urinary Output After a Large Crystalloid Bolus in Healthy Volunteers

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Basic Science Aspects

Ronald P.M. Gonçalves, Karla L. Guarido, Jamil Assreuy, and J. Eduardo da Silva-Santos 415 Gender-Specific Differences in the In Situ Cardiac Function of Endotoxemic Rats Detected by Pressure-Volume Catheter

SDC Supplemental Digital Content is available in the text.

Kimberly J. Riehle, Vicki Hoagland, Whitney Benz, Jean S. Campbell, Denny H. Liggitt, and Lorrie A. Langdale 424 Hepatocellular Heme Oxygenase-1: A Potential Mechanism Of Erythropoietin-mediated Protection After Liver Ischemia-Reperfusion Injury

Anna Starr, Claire A. Sand, Lamia Heikal, Peter D. Kelly, Domenico Spina, Mark Crabtree, Keith M. Channon, James M. Leiper, and Manasi Nandi 432 Overexpression of GTP Cyclohydrolase 1 Feedback Regulatory Protein is Protective in a Murine Model of Septic Shock

SDC Supplemental Digital Content is available in the text.

Wei Xu, Yang Lu, Jihong Yao, Zhenlu Li, Zhao Chen, Guangzhi Wang, Huirong Jing, Xinyuan Zhang, Mingzhu Li, Jinyong Peng, and Xiaofeng Tian 440 Novel Role of Resveratrol: Suppression of High-Mobility Group Protein Box 1 Nucleocytoplasmic Translocation by the Upregulation of Sirtuin 1 in Sepsis-Induced Liver Injury

Joyce A. Bonitz, Julie Y. Son, Benjamin Chandler, Jacquelyn N. Tomaio, Yong Qin, Lauriston M. Prescott, Eleonora Feketeova, and Edwin A. Deitch 448 A Sphingosine-1 Phosphate Agonist (FTY720) Limits Trauma/Hemorrhagic Shock–Induced Multiple Organ Dysfunction Syndrome

Nathan J. White, Xu Wang, Conrad Liles, and Susan Stern 456 Fibrinogen Concentrate Improves Survival During Limited Resuscitation of Uncontrolled Hemorrhagic Shock in a Swine Model

Jing-Jing Zhang, Zong-Ze Zhang, Jian-Juan Ke, Xiang-Hu He, Jia Zhan, Dong-Ling Chen, Yi-Peng Wang, and Yan-Lin Wang 464 Protection Against Intestinal Injury from Hemorrhagic Shock by Direct Peritoneal Resuscitation with Pyruvate in Rats

Francisco Garcia Soriano, Maria Carolina Guido, Hermes Vieira Barbeiro, Elia Garcia Caldini, Clara Batista Lorigados, and Antonio Carlos Nogueira 472 Endotoxemic Myocardial Dysfunction: Subendocardial Collagen Deposition Related to Coronary Driving Pressure

SDC Supplemental Digital Content is available in the text.

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Letters to the Editor

Geoffrey P. Dobson 480 The August Krogh Principle: Seeking Unity in Diversity

Reply: Marcin F. Osuchowski, Peter Radermacher Daniel G. Remick, and Irshad ChaudryThe August Krogh Principle: Seeking Unity in Diversity: Reply

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Commentary

Rosemary Kozar 483 What’s New in Shock, December 2014?

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Clinical Aspects

Monika Dzieciatkowska, Angelo D’Alessandro, Ernest E. Moore, Max Wohlauer, Anirban Banerjee, Christopher C. Silliman, and Kirk C. Hansen 485 Lymph is Not a Plasma Ultrafiltrate: A Proteomic Analysis of Injured Patients

SDC Supplemental Digital Content is available in the text.

Kubra Kamisoglu, Steve E. Calvano, Susette M. Coyle, Siobhan A. Corbett, and Ioannis P. Androulakis 499 Integrated Transcriptional And Metabolic Profiling in Human Endotoxemia

SDC Supplemental Digital Content is available in the text.

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Basic Science Aspects

Angelo D’Alessandro, Monika Dzieciatkowska, Erik D. Peltz, Ernest E. Moore, Janeen R. Jordan, Christopher C. Silliman, Anirban Banerjee, and Kirk C. Hansen 509 Dynamic Changes In Rat Mesenteric Lymph Proteins Following Trauma Using Label-Free Mass Spectrometry

SDC Supplemental Digital Content is available in the text.

Garrett N. Coyan, Michael Moncure, James H. Thomas, and John G. Wood 518 Induced Hypothermia During Resuscitation From Hemorrhagic Shock Attenuates Microvascular Inflammation in the Rat Mesenteric Microcirculation

Jillian R. Richter, Jeffrey M. Sutton, Ritha M. Belizaire, Lou Ann Friend, Rebecca M. Schuster, Taylor A. Johannigman, Steven G. Miller, Alex B. Lentsch, and Timothy A. Pritts 525 Macrophage-derived Chemokine (ccl22) Is a Novel Mediator of Lung Inflammation Following Hemorrhage and Resuscitation

SDC Supplemental Digital Content is available in the text.

Jia-Ren Liu, Xiaohui Han, Sulpicio G. Soriano, and Koichi Yuki 532 The Role of Macrophage 1 Antigen in Polymicrobial Sepsis

Jong-Hau Hsu, Rei-Cheng Yang, Shih-Jen Lin, Shu-Fen Liou, Zen-Kong Dai, Jwu-Lai Yeh, and Jiunn-Ren Wu 540 Exogenous Heat Shock Cognate Protein 70 Pretreatment Attenuates Cardiac and Hepatic Dysfunction With Associated Anti-inflammatory Responses in Experimental Septic Shock

SDC Supplemental Digital Content is available in the text.

Julie Boisramé-Helms, Amissi Said, Mélanie Burban, Xavier Delabranche, Laure Stiel, Fatiha Zobairi, Michel Hasselmann, Valérie Schini-Kerth, Florence Toti, and Ferhat Meziani 548 Medium-chain Triglycerides Supplementation Exacerbates Peritonitis-Induced Septic Shock in Rats: Role on Cell Membrane Remodeling

SDC Supplemental Digital Content is available in the text.

Willson Kwok and Mark G. Clemens 554 Rho-kinase Activation Contributes to Lps-Induced Impairment of Endothelial Nitric Oxide Synthase Activation By endothelin-1 in Cultured Hepatic Sinusoidal Endothelial Cells

Kaiser M. Bijli, Bryce G. Kanter, Mohammad Minhajuddin, Antony Leonard, Lei Xu, Fabeha Fazal, and Arshad Rahman 562 Regulation of Endothelial Cell Inflammation and Lung Polymorphonuclear Lymphocyte Infiltration by Transglutaminase 2

Kazuhiro Shirozu, Shuichi Hirai, Tomokazu Tanaka, Shinsuke Hisaka, Masao Kaneki, and Fumito Ichinose 570 Farnesyltransferase Inhibitor, Tipifarnib, Prevents Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure

Yonghui Yu, Jiake Chai, Haijun Zhang, Wanli Chu, Lingying Liu, Li Ma, Hongjie Duan, Bailing Li, and Dawei Li 578 miR-194 Promotes Burn-Induced Hyperglycemia via Attenuating igf-ir Expression

© 2014 by the Shock Society