Authors: Kenneth Murphy; Paul Travers; Mark Walport
Bibliographic Data: informa Healthcare/Taylor & Francis, 2008. Imprint: Garland Science. ISBN: 978-0-8153-4123-9, 887 pages, soft cover, $95.95.
Reviewer's Expert Opinion:
Description: This highly regarded comprehensive textbook of basic immunology covers the different mechanisms used by the immune system to protect the host from infections as well as other aspects of immunology including allergy, autoimmunity, transplant and tumor immunology. This seventh edition has been updated throughout, with new information on topics such as NK cells, Toll-like receptors, viral evasins, innate receptors, and celiac disease. Purpose: The purpose is to present in a comprehensive, yet concise manner the current knowledge on basic immunology from the viewpoint of the host's interaction with potentially harmful microbes in its environment. Audience: This is intended as an introductory immunology text for medical students, postgraduate students, and scientists interested in the field of immunology. It is especially useful for immunology trainees seeking current and accurate information on the immune system and for immunologists for quick reference and teaching preparation. Features: The book begins with an introduction on immunobiology and innate immunity, followed by sections on antigen recognition, development of lymphocyte receptor repertoires, adaptive immune response, immune system in health and disease, and evolutionary history of the immune system. The appendix contains sections on diagnostic tools and summary tables on CD antigens and cytokines. There is also an easy to use glossary. The chapters are well ordered and the language is clear and succinct. Ample, well-designed diagrams and tables illustrate complex ideas. Summary paragraphs further consolidate the topics discussed. Each chapter concludes with revision questions and a well organized list of references. The accompanying CD containing animations, voiceover narration, and all the figures in the book in the format of a PowerPoint presentation, is an invaluable resource. Assessment: This is one of the best basic immunology textbooks available. Materials are well organized and clearly presented. It is a must-have for clinicians and researchers who strive to have an understanding of basic immunology.
Reviewer: Denise Chee Hsu, BSc, MBBS (Campbelltown Hospital)