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Book Reviews

Sepsis and Multiple Organ Dysfunction: A Multidisciplinary Approach

Dries, David J. MD, Reviewer

Section Editor(s): Dries, David J. Book Review Editor

Author Information
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Sepsis and Multiple Organ Dysfunction: A Multidisciplinary Approach Editors: Edwin A. Deitch, MD; Jean-Louis Vincent, MD, PhD; Alastair Windsor, MD, FRCS Bibliographic Data: Elsevier Science Publishing Company, 2002. Imprint: W.B. Saunders Company. ISBN: 0-7020-2165-2, 497 pp, hard cover, $99.95.

Reviewer's Expert Opinion:


This 58-chapter multiauthor book focuses on organ failure in the setting of critical illness with varied etiologies.


A central goal is integration of new information on the basic biology of sepsis and multiple organ dysfunction and to focus attention on therapeutic consequences of recent advances in our understanding of this syndrome.


Trainees and practitioners in critical care are an appropriate audience for this work. Contributors are international authorities in multiple organ dysfunction and combine their talents effectively in this work.


The book follows a traditional organization with early presentation of epidemiology and hypotheses regarding etiology of multiple organ dysfunction. Scoring systems and management principles follow with specific discussion of individual organ system support. Multiorgan issues including pharmacokinetics, sedation, analgesia, and related medication administration are discussed in concluding chapters. Presentations are clearly written and use line drawings and tables to good effect. Each chapter contains a reference list of primary contributions dating to within two years of publication. The table of contents groups chapters by major subject headings and provides authorship. A subject index of seven pages provides adequate access to content. Assessment: This is an effective combination of insights from authors and editors with established expertise in this arena. At present, this is the most current and leading textbook on this subject.

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