Wound Healing: Methods and Protocols
Editors: Luisa A. DiPietro, DDS, PhD; Aime L. Burns Bibliographic Data: Humana Press Inc., 2003. ISBN: 0-896039-99-4, 467 pp, hard cover, $135.00.
Reviewer's Expert Opinion:
This is an overview of techniques and models for assessment of wound healing. It is part of the Methods in Molecular Medicine series published by Humana Press.
Presented is a sample of techniques involving many of the available experimental models of wound healing.
Clinical and basic science researchers with an interest in wound healing of various kinds are an appropriate audience for this work. Editors and authors represent some of the leading wound healing laboratories in the United States with a smaller number of presentations from overseas.
The 34 chapters in this book are divided into two general parts beginning with experimental models of wound healing. Some chapters in this first portion describe, in cookbook fashion, execution of experiments of various kinds. Other chapters describe the rationale behind specific model systems such as the issues of wound repair in diabetes or with aging. A collection of chapters, comprising approximately one third of the book, describes specific analytic techniques to understand the wound healing process. These chapters include considerations such as measurement of oxygen tension, detection of cytokine protein in tissue, endothelial cell migration and evaluation of angiogenesis. Chapters are written in a straightforward manner, though the format varies depending on the type of chapter. Black-and-white line drawings are used to good effect. Where black-and-white photographs are employed, quality is less consistent. Chapters conclude with a reference list containing original citations. Where reviews of a subject are presented, references include original work dating to within two years of publication. The table of contents groups chapters by type and provides authorship. A concluding subject index provides adequate access to content.
This book is a collection of techniques and insights which belongs on the shelf of laboratories or research organizations having an interest in wounds.