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Clostridium difficile infection: a review

Kouhsari, Ebrahima; Abbasian, Saraa; Sedighi, Mansoura; Yaseri, Hashem F.b; Nazari, Shahramc; Bialvaei, Abed Z.a; Dahim, Parisad; Mirzaei, Elnaze Z.e; Rahbar, Mohammadf

Reviews in Medical Microbiology: July 2018 - Volume 29 - Issue 3 - p 103–109
doi: 10.1097/MRM.0000000000000135
BACTERIOLOGY

Clostridium difficile, as one of the main bacterial causes of diarrhea, is an important healthcare-associated pathogen. It is also the main causative agent of antibiotic-associated diarrhea and pseudomembranous colitis. The C. difficile infection is a life threatening disease, and there is an urgent need to control its spread in healthcare centers. This review summarizes the most recent work on epidemiology and interactions between host and C. difficile.

aDepartment of Microbiology, Faculty of Medicine

bDepartment of Internal Medicine, Firouzgar Hospital, Iran University of Medical Sciences, Tehran

cDepartment of Environmental Health Engineering, Qom University of Medical Sciences, Qom

dDepartment of Quality Management and Laboratory Accreditation, Reference Health Laboratories Research Center, Ministry of Health and Medical Education, Tehran

eDepartment of Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol

fDepartment of Microbiology, Iranian Reference Health Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran.

Correspondence to Dr Mohammad Rahbar, PhD, Professor of Microbiology, Department of Microbiology, Iranian Reference Health Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran. Tel: +98 021 66728112; fax: +98 021 66728121; e-mail: rahbar.reflab@gmail.com

Received 22 February, 2018

Accepted 12 March, 2018

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