BACTERIOLOGYPersistence of Mycobacterium bovis under environmental conditions is it a real biological risk for cattle?Rodríguez-Hernández, Elbaa; Pizano-Martínez, Oscar E.b; Canto-Alarcón, Germinalc; Flores-Villalva, Susanaa; Quintas-Granados, Laura I.d; Milián-Suazo, FelicianocAuthor Information aNational Center for Disciplinary Research in Physiology and Animal Improvement – INIFAP, Colon, Qro bDepartment of Medical Clinics, Research Institute in Reumatology and Esqueletum Muscle System, CUCS, University of Guadalajara, Guadalajara, Jalisco cFaculty of Natural Sciences, Autonomous University of Querétaro, Querétaro dGraduate Program in Genomic Sciences, Autonomous University of Mexico City, Mexico D.F., Mexico. Correspondence to Feliciano Milián-Suazo, PhD, Faculty of Natural Sciences, Autonomous University of Queretaro, Sciences Avenue Juriquilla, Santa Rosa Jauregui Delegation, CP 76230 Queretaro, Mexico. Tel: +442 1921200, x5384; e-mail: [email protected] Received 8 May, 2015 Revised 9 June, 2015 Accepted 9 June, 2015 Reviews in Medical Microbiology: January 2016 - Volume 27 - Issue 1 - p 20-24 doi: 10.1097/MRM.0000000000000059 Buy Metrics Abstract Mycobacterium bovis has a wide range of hosts. Usually, it affects cattle; however, it has been detected in humans and many wildlife reservoirs such as cervids, badgers, feral pigs, brushtail possums, and buffaloes. Persistence in wildlife has made it difficult to eradicate M. bovis, even in developed countries. The main route of M. bovis transmission is by aerosol through the respiratory tract; direct contact between cattle and wildlife is the explanation for transmission between species. However, depopulated farms have experienced recontamination after cleaning and disinfecting and months of not having cattle, suggesting persistence of M. bovis in contaminated plants, soil, and water. The question remains as to whether M. bovis persists in the environment for long periods of time and is capable of causing new outbreaks. We show that M. bovis in the environment is a risk for cattle if some key environmental conditions are present: appropriate substrate, temperature, desiccation, and sunlight. Copyright © Wolters Kluwer Health, Inc. All rights reserved.