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Chryseobacterium indologenes carrying blaIND-1 isolated from blood obtained from a patient with adenocarcinoma: a case report and minireview of the literature

Ojdana, Dominikaa,*; Gińdzieńska-Sieśkiewicz, Ewab,*; Sacha, Paweła,*; Wieczorek, Piotra; Krawczyk, Malgorzatac; Kita, Karolb; Michalska, Annaa; Sierakowski, Stanisłlawb; Tryniszewska, Elżbietaa

Reviews in Medical Microbiology: July 2015 - Volume 26 - Issue 3 - p 119–124
doi: 10.1097/MRM.0000000000000043

Chryseobacterium indologenes is an environmental organism and is an uncommon human pathogen. This causes opportunistic infections in patients with severe underlying clinical conditions. C. indologenes infections are problematic because of decreased therapeutic options attributable to bacterial resistance to antibiotics, which mainly depend on the production of the specific IND type of metallo-β-lactamases. We report a case of C. indologenes in a blood sample obtained from a patient with adenocarcinoma. The patient was treated with a 1.2-g dose of Augmentin three times a day. The treatment was followed by normalization of the patient's temperature. The patient was finally transferred to the surgery department for further investigation. Molecular biology revealed that the tested strain carried the blaIND-1 gene, which is responsible for the production of the IND-1 type of metallo-β-lactamase. To the best of our knowledge, this is the first description of IND-1-producing C. indologenes bacteraemia in Poland.

aDepartment of Microbiological Diagnostics and Infectious Immunology

bDepartment of Rheumatology and Internal Medicine, Medical University of Bialystok

cDepartment of Microbiological Diagnostics and Infectious Immunology, University Hospital of Bialystok, Bialystok, Poland.

*Dominika Ojdana, Ewa Gińdzieńska-Sieśkiewicz, and Poweł Sacha contributed equally to the writing of this article.

Correspondence to Dominika Ojdana, Department of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Waszyngtona Street 15a, 15-269 Bialystok, Poland. Tel: +48 85 746 87 46; fax: +48 85 746 85 71; e-mail:

Received 25 January, 2015

Revised 9 February, 2015

Accepted 9 February, 2015

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