MICROBIAL INFECTIONInfections with the novel human bocavirusNaghipour, Mohammadrezaa,b,c; Hart, C Anthonya; Cuevas, Luis Ea,cAuthor Information From the aSchool of Infection and Host Defence, University of Liverpool, UK bGuilan University of Medical Sciences, Rasht, Iran cLiverpool School of Tropical Medicine, UK. Received 17 May, 2007 Revised 29 May, 2007 Accepted 12 June, 2007 Correspondence to L. E. Cuevas, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK. Tel: +44 (0)151 705 3219; fax: +44 (0)151 705 3329; e-mail: [email protected] Reviews in Medical Microbiology: January 2007 - Volume 18 - Issue 1 - p 5-10 doi: 10.1097/MRM.0b013e3282e1c680 Buy Metrics Abstract Human bocavirus is a newly described pathogen associated with acute respiratory infections and perhaps diarrhoeal disease. The majority of infections are reported in young children and often in the presence of other respiratory pathogens. Case series have increasingly been reported worldwide, suggesting that the virus may have a high frequency in children and that other clinical presentations beyond the respiratory tract may have to be considered. This review summarizes the worldwide distribution, epidemiological characteristics and clinical presentations of human bocavirus and discusses the evidence of it's pathogenic role during infection. © 2007 Lippincott Williams & Wilkins, Inc.