MRSA INFECTION AND ITS CONTROLFuture shape of MRSA infection and its controlGemmell, Curtis GAuthor Information From the Division of Immunology, Infection and Inflammation, Medical School, University of Glasgow and MRSA Reference Laboratory, Glasgow, UK. Correspondence to C. G. Gemmell, Division of Immunology, Infection and Inflammation, Medical School, University of Glasgow, Department of Bacteriology, Glasgow Royal Infirmary, Glasgow, 94 OSF. Tel: +44 (0)141 211 4654; fax: +44 (0)141 552 1524; e-mail: [email protected] Reviews in Medical Microbiology: August 2006 - Volume 17 - Issue 3 - p 83-87 doi: 10.1097/MRM.0b013e3280112c43 Buy Metrics Abstract Methicillin resistance has been recognized in Staphylococcus aureus since the 1960s and is now endemic worldwide. Resistance to this antibiotic and several others have made methicillin-resistant Staphylococcus aureus (MRSA) a major cause of infection. It is now a significant cause of infection in the community as happened some 30 years ago with penicillin resistance in the same bacterial pathogen. Considerable effort is now being devoted to the development of better ways of controlling infection. These include changes in hospital management, prudent appropriate use of antibiotics and development of new modalities for treatment of infection. This review will attempt to forecast the future picture of MRSA infection and its control over the next 10–15 years. The value and possible impact of new antibiotics with novel modes of action, vaccines and antibodies will be discussed. © 2006 Lippincott Williams & Wilkins, Inc.