Original ArticlesSPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS AFTER INDOCYANINE GREEN-ASSISTED VITRECTOMY FOR IDIOPATHIC MACULAR HOLESayanagi, Kaori MD; Sharma, Sumit MS; Kaiser, Peter K. MDAuthor Information From the Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio. Dr. Sayanagi has no proprietary interest in any aspect of this report. Mr. Sharma has received travel funding from Reichert Inc., and Dr. Kaiser serves on the Scientific Advisory Boards of Heidelberg and Carl Zeiss Meditec. Reprint requests: Peter K. Kaiser, MD, Cole Eye Institute, The Cleveland Clinic Foundation, 9,500 Euclid Avenue, Desk i3, Cleveland, OH 44195; e-mail: firstname.lastname@example.org Retinal Cases & Brief Reports: April 2009 - Volume 3 - Issue 2 - p 109-111 doi: 10.1097/ICB.0b013e31818a4721 Buy Metrics AbstractIn Brief Purpose: To report the intraretinal changes seen on the spectral-domain optical coherence tomography after indocyanine green (ICG) assisted internal limiting membrane peeling for macular hole. Methods: A 76-year-old woman with closed macular hole after ICG-assisted internal limiting membrane peeling presented poor visual acuity. Infrared-red, fundus autofluorescence, ICG fluorescence, time-domain OCT and spectral-domain optical coherence tomography images were obtained. Results: Spectral-domain optical coherence tomography showed the irregular bumps of the retinal pigment epithelium, thinning of the overlying photoreceptor inner and outer segment layer, and enhanced reflectivity of external limiting membrane layer that corresponded to residual ICG fluorescence dots. The area of retinal pigment epithelium changes and inner and outer segment layer disruption seemed to correspond to residual ICG fluorescence in the previous macular hole bed. Conclusion: The intraretinal changes were observed in areas of retained ICG after ICG-assisted internal limiting membrane peeling. Spectral-domain optical coherence tomography detected these changes clearly. The intraretinal changes were observed in areas of retained ICG after ICG-assisted internal limiting membrane peeling. Spectral-domain optical coherence tomography detected these changes clearly. © 2009 Ophthalmic Communications Society, Inc.