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Astroz, Polina, MD*; Miere, Alexandra, MD*; Cohen, Salomon Yves, MD, PhD*,†; Querques, Giuseppe, MD, PhD*,‡; Souied, Eric H., MD, PhD*

doi: 10.1097/ICB.0000000000000741
Case Report: PDF Only

Purpose: To describe optical coherence tomography angiography (OCTA) findings in retinal arterial macroaneurysm (RAM) associated with macular edema and to correlate OCTA findings with conventional multimodal imaging.

Methods: The clinical course, conventional multimodal imaging findings including fundus color photography, spectral domain optical coherence tomography (Spectralis; Heidelberg Engineering, Heidelberg, Germany), fluorescein angiography (Heidelberg Engineering), and OCTA (Optovue, Inc, Freemont, CA) findings at baseline and during the follow-up of two eyes (two patients) with symptomatic RAM associated with macular edema were documented.

Results: Two eyes of 2 patients, both women, aged 82 and 46 years, which presented with progressive visual decline, were included. On conventional multimodal imaging, exudative RAM with macular edema and lipid exudation were visible in both included eyes. On OCTA, the flow in the two RAM was detected at baseline. Case 1 was treated by focal laser photocoagulation. One month after treatment, fluorescein angiography showed RAM occlusion. Spectral domain optical coherence tomography showed a RAM and retinal thinning and a decreased central foveal thickness, resulting in visual acuity improvement. On OCTA, no flow was detectable in the RAM at 1-month follow-up. Case 2 was not treated at baseline. In this eye, no flow was detected on OCTA at 2-month follow-up. This suggests a spontaneous occlusion, which was confirmed by fluorescein angiography.

Conclusion: Optical coherence tomography angiography is able to detect the presence or absence of flow signal within RAMs, which may both decrease the need for dye angiography in selected cases with exudative RAM and help in treatment decision making.

Optical coherence tomography angiography is able to detect the flow within the retinal arterial macroaneurysm and its thrombosis. Optical coherence tomography angiography could be useful in the diagnosis and follow-up of retinal arterial macroaneurysm allowing for prompt and appropriate management of this sight-threatening lesion.

*Department of Ophthalmology, Intercity Hospital and University Paris Est, Créteil, France;

Centre Ophtalmologique d'Imagerie et de Laser, Paris, France; and

Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy.

Reprint requests: Eric H. Souied, MD, PhD, Department of Ophthalmology, University Paris Est Créteil, Centre Hospitalier Intercommunal de Créteil, Créteil, France; e-mail:

None of the authors has any financial/conflicting interests to disclose.

© 2019 by Ophthalmic Communications Society, Inc.