Case Report: PDF OnlyEfficacy of Intravitreal Aflibercept Injections in the Treatment of Idiopathic Retinal Vasculitis, Aneurysms and Neuroretinitis SyndromeJones, Anthony A. BS1; Morgenstern, Joshua L. BA2; Mandair, Divneet MD, MS3; Pedler, Michelle G. BSc (Hons)2; Olson, Jeffrey L. MD2Author Information 1Department of Medicine, Rocky Vista University College of Osteopathic Medicine, Parker, Colorado, USA 2Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado, USA 3Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA Corresponding Author: Jeffrey Olson, MD, Rocky Mountain Lions Eye Institute, 1675 Aurora Court, Mailstop F731, Aurora, CO 80045, (720) 848-2500, (720) 848-5014 fax The authors hold no proprietary interest or have any conflicts, or potential conflicts. Retinal Cases & Brief Reports: June 08, 2020 - Volume - Issue - doi: 10.1097/ICB.0000000000001020 Buy PAP Metrics Abstract Purpose: To present a case of IRVAN syndrome that was successfully managed with serial intravitreal aflibercept injections. Methods: Ophthalmic imaging and visual acuity were used to monitor disease state and track treatment methods in order to determine the most valuable combination of treatment medication and treatment interval. Results: 25-year-old woman with IRVAN syndrome status post panretinal photocoagulation of both eyes presented with bilateral cystoid macular edema (CME). We demonstrate successful management of retinal CME associated with idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome using serial intravitreal aflibercept injections. Conclusion: Intravitreal aflibercept has a useful role in managing the potential retinal complications associated with IRVAN syndrome and provides further insight into treatment of the later stages of this rare disease. © 2021 by Ophthalmic Communications Society, Inc.