Case Report: PDF OnlyCone Photoreceptor Integrity assessed with Adaptive Optics Imaging after Laser-Pointer-Induced Retinal InjuryVitellas, Carol BA1; Doble, Nathan PhD2,3; Wells-Gray, Elaine M. PhD2; Challa, Nayanika BA1; Davidorf, Frederick MD3; Choi, Stacey S. PhD2,3Author Information 1The Ohio State University, College of Medicine, 370 W 9th Ave, Columbus, OH 43210. 2The Ohio State University, College of Optometry, 338 W 10th Ave, Columbus, OH, USA 43210. 3The Ohio State University, Department of Ophthalmology and Visual Science, Havener Eye Institute, 915 Olentangy River Road, Columbus, OH, USA 43212. Corresponding Author: Nathan Doble, PhD, The Ohio State University, College of Optometry, 338 W 10th Ave, Columbus, OH, USA 43210. E-mail: [email protected] Telephone: 614-688-2052 The authors have no relevant financial interests and no potential conflicts of interest to disclose. Retinal Cases & Brief Reports: June 08, 2020 - Volume - Issue - doi: 10.1097/ICB.0000000000001025 Buy PAP Metrics Abstract Purpose: To examine the three-dimensional foveal cone photoreceptor structure in a patient who had suffered laser pointer induced retinal injury. Methods: Patient underwent standard fundus photography and clinical spectral domain optical coherence tomography (SD-OCT) imaging. High-resolution imaging was performed using an Adaptive Optics-OCT-Scanning Laser Ophthalmoscope (AO-OCT-SLO). Results: AO imaging revealed loss of inner and outer segments of cone photoreceptors while the anterior retinal layers appeared healthy. Analysis of cone topology showed an increase in Voronoi domain area and a less regular hexagonal packing structure closer to the lesion site. Conclusion: Exposure to laser pointer radiation, however brief, can result in damage to the retina. Here, repeated imaging nine months later showed a decrease in the size of the lesions (ranging from 3.7 to 23.9%) compared to the first time point. However, the longer-term prognosis is likely permanent scarring. © 2021 by Ophthalmic Communications Society, Inc.