Case ReportEXUDATIVE RETINAL DETACHMENT DOCUMENTED BY HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AFTER RETINAL LASER PHOTOCOAGULATION FOR RETINOPATHY OF PREMATURITYCabrera, Michelle T. MD*,†; Brewer, Erika M. MD‡; Grant, Laura MD§; Tarczy-Hornoch, Kristina MD, DPhil*,†Author Information *Department of Ophthalmology, Seattle Children's Hospital, Seattle, Washington; †Department of Ophthalmology, University of Washington, Seattle, Washington; ‡Department of Ophthalmology, University of Arizona, Tucson, Arizona; and §Department of Ophthalmology, Henry Ford Health System, Detroit, Michigan. Reprint requests: Michelle T. Cabrera, MD, OA.9.220, 4800 Sand Point Way NE, Seattle, WA 98105; e-mail: [email protected] Supported by an unrestricted grant from Research to Prevent Blindness to the Department of Ophthalmology at the University of Washington. None of the authors has any financial/conflicting interests to disclose. Retinal Cases & Brief Reports: May 2021 - Volume 15 - Issue 3 - p 310-313 doi: 10.1097/ICB.0000000000000793 Buy Metrics AbstractIn Brief Background: Few cases of exudative retinal detachments have been reported in the literature after laser treatment for retinopathy of prematurity, and none of the cases include optical coherence tomography images. Methods: Case report. Results: A 469-g birth weight, 25-week gestational age baby girl at 35-week postmenstrual age received a retinal laser (1,724 spots in the right eye and 1,287 spots in the left eye) for bilateral Stage 3 Zone II plus disease retinopathy of prematurity. The patient developed a large macular exudative retinal detachment seen in the right eye at the first follow-up, 5 days after the laser. Serial handheld optical coherence tomography demonstrated resolution of retinal detachment and intraretinal fluid over the course of 4 weeks with only topical tobramycin/dexamethasone ophthalmic ointment 3 to 4 times daily for 2 weeks. The patient was left with a residual subretinal scar and outer retinal loss on optical coherence tomography, with a later appearance of a dragged macula on funduscopic examination noted at 52-week postmenstrual age. It is unclear whether systemic steroid therapy, intravitreal bevacizumab, or surgery would hasten resolution of exudative retinal detachment after the retinopathy of prematurity laser and avoid photoreceptor damage seen on optical coherence tomography in this case. Conclusion: This case suggests that post–retinopathy of prematurity laser exudative retinal detachments can resolve without aggressive intervention, but may cause permanent retinal sequelae. We report a case of an infant who developed unilateral exudative retinal detachment after retinal laser photocoagulation for Type 1 retinopathy of prematurity. Handheld spectral domain optical coherence tomography documented resolution within 1 month on topical corticosteroid therapy alone but with significant photoreceptor loss.