Case ReportMULTIMODAL IMAGING OF CHOROIDAL AND OPTIC DISK VESSELS NEAR OPTIC DISK PITSAdams, Matthew K. MD, MBA*; Cohen, Salomon-Yves MD, PhD†; Souied, Eric H. MD, PhD‡; Goldenberg, Dafna MD§; Loewenstein, Anat MD, MHA§; Olsen, Timothy W. MD*; Pulido, Jose S. MD, MS, MBA, MPH*,¶Author Information *Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota; †Ophthalmic Center for Imaging and Laser, Paris, France; ‡Department of Ophthalmology, University of Paris Est Creteil, Paris, France; §Department of Ophthalmology, Tel Aviv Medical Center, University of Tel Aviv, Tel Aviv, Israel; and ¶Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota. Reprint requests: Jose S. Pulido, MD, MS, MBA, MPH, Departments of Ophthalmology and Molecular Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905; e-mail: firstname.lastname@example.org Supported in part by unrestricted grants from Research to Prevent Blindness, Inc, New York, New York, and from grants from the Deshong and Paul Family (J.S.P.). J. S. Pulido has stock in LAgen Laboratories, which supplies induced pluripotent stem cell-derived RPE cells for in vitro studies, and has no relevant financial interests. The remaining authors have no conflicting interests to disclose. Retinal Cases & Brief Reports: Fall 2020 - Volume 14 - Issue 4 - p 289-296 doi: 10.1097/ICB.0000000000000765 Buy Metrics AbstractIn Brief Purpose: To describe modern multimodal imaging of the choroidal and optic disk vessels in optic disk pits. Methods: Case reports of four patients with optic disk pit who underwent multimodal imaging of the optic pit and surrounding structures. Patients included in this article were found to have optic disk pits and subsequently underwent multimodal imaging. Results: Cilioretinal arteries were present in two of the four cases (50%). SPECTRALIS optical coherence tomography showed intraretinal and subretinal fluid in all cases. Small vessels in the choroid and in the disk around the pit were also present in all cases through optical coherence tomographic angiography. Confocal fluorescein angiographic imaging in the first case showed leakage from the vessels adjacent to the optic disk pit. Conclusion: Modern multimodal imaging shows that there are anomalous vessels in and around an optic pit. Whether these vessels affect the development of optic pit, maculopathy needs to be further evaluated. Four patients (four eyes) were found to have optic disk pits and subsequently underwent multimodal imaging. All patients were found to have abnormal vessels within and adjacent to the optic disk pit. One case revealed leakage from these abnormal vessels. The role of this irregular vasculature should be further investigated.