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SEVERE PANUVEITIS, RETINAL VASCULITIS, AND OPTIC DISK GRANULOMA SECONDARY TO SARCOIDOSIS

Patterson, Michael, DO*; Bergstrom, Chris S., MD, OD; Clark, W. Lloyd, MD*,‡; Grossniklaus, Hans E., MD; Payne, John F., MD*,‡

Retinal Cases and Brief Reports: October 2016 - Volume 10 - Issue 4 - p 341–344
doi: 10.1097/ICB.0000000000000254
Case Report
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Purpose: To report a case of panuveitis, retinal vasculitis, and optic disk granuloma due to sarcoidosis.

Methods: Case report and literature review.

Results: A 26-year-old previously healthy African American male presented with four months of gradual progressive visual decline in the right eye. Clinical examination revealed severe panuveitis, retinal vasculitis, and large optic nerve mass lesion. Diffuse supraclavicular lymphadenopathy was also present. Histopathologic examination of the lymph node biopsy revealed granulomatous inflammation with some areas of caseous necrosis consistent with sarcoidosis.

Conclusion: Sarcoidosis is a common cause of uveitis and retinal vasculitis. In rare cases, an optic disk granuloma may occur and can be treated with immunosuppressive therapy.

The patient presented with profound painless vision loss in the right eye and was found to have severe panuveitis, retinal vasculitis, and optic disk granuloma due to sarcoidosis. The disease was managed with immunosuppressive therapy consisting of corticosteroids and adalimumab.

*Department of Ophthalmology, University of South Carolina, Columbia, South Carolina;

Department of Ophthalmology, Emory Eye Center, Atlanta, Georgia; and

Palmetto Retina Center, West Columbia, South Carolina.

Reprint requests: John F. Payne, MD, Palmetto Retina Center, 124 Sunset Court, West Columbia, SC 29169; e-mail: jpayne@palmettoretina.com

The information contained in this article was presented at the 2013 annual meeting of The Retina Society in Beverly Hills, CA.

None of the authors have any financial/conflicting interests to disclose.

© 2016 by Ophthalmic Communications Society, Inc.