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Gupta, Pawan MD; Jain, Chikirsha MD; Aggarwal, Ankur MD; Gupta, Satish Chand MD

Retinal Cases and Brief Reports: July 2011 - Volume 5 - Issue 3 - p 213-218
doi: 10.1097/ICB.0b013e3181e72348
Case Report

Purpose: To report ocular manifestations in cases of previously undiagnosed dengue fever.

Methods: A retrospective study was done to evaluate the cause of sudden painless loss of vision in three cases with history of fever. Detailed systemic evaluation and ophthalmologic examination consisting of fundus photographs, fundus fluorescein angiography, and optical coherence tomography were done, where needed.

Results: All three patients tested positive for dengue serology, which had been undiagnosed earlier. Retinal hemorrhages were found in all three patients, while one patient also showed evidence of retinitis-like lesions. He was treated with oral steroids and showed improvement in visual acuity over a period of 6 weeks. Two of the three patients had subhyaloid hemorrhages, which were seen to resolve spontaneously.

Conclusion: A significant subset of patients with mild form of dengue fever may go undiagnosed.

We report an observational case series of five eyes (three patients) with sudden, painless, diminution of vision and a history of fever. Patients had retinal and subhyaloid hemorrhages in the macula. None was diagnosed previously as dengue fever. Ophthalmologists should be aware of ocular manifestations of dengue fever, especially in endemic areas.

From the Vitreo Retina and Uveitis, Venu Eye Institute and Research Centre, New Delhi, India.

The authors received no financial support.

None of the authors have any financial interest in the company/equipment used in the study.

Reprint requests: Pawan Gupta, MD, Vitreo Retina and Uveitis, Venu Eye Institute and Research Centre, 1/31, Sheikh Sarai Institutional Area Phase 2, New Delhi 110017, India; e-mail:

© 2011 Ophthalmic Communications Society, Inc.