To describe an ocular manifestation of Castleman disease, a rare lymphoproliferative disorder characterized by sheets of abundant plasma cells in the interfollicular spaces of lymph nodes, most commonly in the abdomen, mediastinum, and cervical chain.
Clinicopathologic case report.
A 69-year-old man with lymphadenopathy and bilateral choroidal infiltrates.
Initially, we suspected systemic lymphoma with ocular involvement. Lymph node biopsy revealed Castleman disease without a monoclonal component. Choroidal biopsy showed lymphocytic and plasma cell infiltration.
To our knowledge, this is the first clinicopathologic report of multicentric Castleman disease involving the eye.