A FACTOR FOUND IN THE IGG FRACTION OF SERUM OF PATIENTS WITH PARANEOPLASTIC BILATERAL DIFFUSE UVEAL MELANOCYTIC PROLIFERATION CAUSES PROLIFERATION OF CULTURED HUMAN MELANOCYTES Miles, Sarah L.; Niles, Richard M.; Pittock, Sean; More Miles, Sarah L.; Niles, Richard M.; Pittock, Sean; Vile, Richard; Davies, John; Winters, Jeffrey L.; Abu-Yaghi, Nakhleh E.; Grothey, Axel; Siddiqui, Mustaqeem; Kaur, Judith; Hartmann, Lynn; Kalli, Kimberly R.; Pease, Larry; Kravitz, Daniel; Markovic, Svetomir; Pulido, Jose S. Less RETINA. 32(9):1959-1966, October 2012. Abstract Abstract In Brief In Brief Favorites PDF Get Content & Permissions Abstract: In Brief: Bilateral diffuse uveal melanocytic proliferation is a paraneoplastic condition characterized by proliferation of uveal melanocytes. We show that cultured melanocytes and melanoma cells proliferate once they are exposed to the serum or plasma of these patients. The activity appears to be concentrated in the IgG fraction.