Original ArticlesMULTIFOCAL RETINAL CONTRACTION IN MACULAR PUCKER ANALYZED BY COMBINED OPTICAL COHERENCE TOMOGRAPHY/SCANNING LASER OPHTHALMOSCOPYGUPTA, PRIYA BS*†; SADUN, ALFREDO A. MD, PhD†; SEBAG, J MD, FACS, FRCOphth*†Author Information From *VMR Institute, Huntington Beach; and †Doheny Eye Institute, University of Southern California Keck School of Medicine, Los Angeles. None of the authors has a proprietary interest in this study. Presented as a paper at the 19th Annual Western Retina Study Club Meeting; Pasadena, California; March 17, 2007. Reprint requests: J. Sebag, MD, FACS, FRCOphth, VMR Institute, 7677 Center Avenue, Suite 400, Huntington Beach, CA 92647. e-mail:[email protected] Retina: March 2008 - Volume 28 - Issue 3 - p 447-452 doi: 10.1097/IAE.0b013e318160a754 Buy Metrics AbstractIn Brief Purpose: To characterize the topography of macular pucker using coronal plane imaging in vivo, and correlate this with transverse optical coherence tomography (OCT) to assess the relationship between topographic features and severity of disease. Methods: Forty-four eyes with macular pucker underwent full ophthalmologic evaluation including B-scan ultrasonography as well as coronal and transverse plane imaging with combined OCT/scanning laser ophthalmoscopy (SLO). Results: Posterior vitreous detachment was present in 37/44 eyes (84.1%) by ultrasound. Multiple foci of retinal contraction were detected in 20/44 eyes (45.5%) by coronal plane OCT/SLO. Intraretinal cysts were present in 6/9 (66.7%) eyes with three or four contraction centers as compared to 10/35 (28.6%) eyes with one or two contraction centers (P = 0.05). Eyes with three or four contraction centers had significantly (P = 0.05) thicker maculae (369 ± 98 μm) compared to those with one or two contraction centers (297 ± 110 μm). Conclusion: Coronal plane imaging detected multifocality in nearly half of eyes with macular pucker. Eyes with multiple retinal contraction centers had greater retinal damage compared to eyes with one or two contraction centers. Multifocal retinal contraction may have clinical significance in that it may impact on prognosis and management. Optical coherence tomography/scanning laser ophthalmoscopy imaging of macular pucker revealed multifocal retinal contraction and identified increased retinal damage with more foci of retinal contraction. © The Ophthalmic Communications Society, Inc.