^*Departments of Ophthalmology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan

^†NESMOS Department, Ophthalmology Unit, S. Andrea Hospital, Sapienza University of Rome, Italy

^‡Retina Associates, Sydney, Australia

^§Department of Ophthalmology, NYU Grossman School of Medicine, New York, New York

^¶Saratoga Ophthalmology, Malta, New York

^**Vitreous Retina Macula Consultants of New York, New York, New York

Supported by the Macula Foundation Inc, New York, NY. The funding bodies had no role in the design or execution of this work or the decision to publish.

Y. Sakurada: a lecturer: Novartis, Bayer, Kowa, Santen. K. B. Freund: a consultant to Zeiss, Bayer, Novartis, Allergan, and Heidelberg Engineering and receives research support from Genentech/Roche. None of the other authors has any financial/conflicting interests to disclose.