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THE RELATIONSHIP BETWEEN FOVEAL AVASCULAR ZONE AREA, VESSEL DENSITY, AND CYSTOID CHANGES IN DIABETIC RETINOPATHY: AN OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY

Tarassoly, Kia, MD; Miraftabi, Arezoo, MD; Soltan Sanjari, Mostafa, MD; Parvaresh, Mohammad Mehdi, MD

doi: 10.1097/IAE.0000000000001755
Original Study

Purpose: To measure the foveal avascular zone (FAZ) areas and vessel densities of patients with diabetic retinopathy and to study their relationship with diabetic cystoid changes and retinal thickness.

Methods: Prospective case series of 51 eyes of 31 patients with diabetic retinopathy. The eyes were grouped based on the presence or absence of cystoid edema and evaluated using optical coherence tomography angiography. The FAZ areas and vessel density were compared.

Results: The FAZ area at the superficial capillary plexus level was equal between the eyes with and without cystoid edema. Vessel density did not differ as well. There was no correlation with retinal thickness. In eyes with cystoid changes, FAZ area changes at the deep capillary plexus level were difficult to interpret.

Conclusion: The FAZ area and vessel density at the superficial capillary plexus level are reproducible and independent of the presence of cystoid edema.

Using optical coherence tomography angiography, the foveal avascular zone area and vessel density are compared between eyes with diabetic cystoid changes and eyes with diabetic retinopathy but no cystoid changes.

Department of Ophthalmology, Eye Research Center, Rasoul-Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Reprint requests: Kia Tarassoly, MD, Department of Ophthalmology, Rasoul-Akram Hospital, Iran University of Medical Sciences (IUMS), Sattarkhan-Niayesh Street, Tehran, Iran 14456-13131; e-mail: kiatarassoly@gmail.com

None of the authors has any financial/conflicting interests to disclose.

© 2018 by Ophthalmic Communications Society, Inc.