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POSTERIOR PRECORTICAL VITREOUS POCKETS IN HIGH MYOPIA OBSERVED BY ENHANCED VITREOUS IMAGING OF SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Wang, Xiaohan, MD*; Shen, Mengxi, MD*; Wang, Ruoshi, MD*; Zhou, Yanping, MD*; Li, Tong, MD*; Xiao, Meichun, MD*; Song, Minlu, MD*; Sun, Xiaodong, MD, PhD*,†,‡; Wang, Fenghua, MD*,‡

doi: 10.1097/IAE.0000000000002101
Original Study: PDF Only

Purpose: To observe the vitreous in highly myopic eyes with posterior precortical vitreous pockets (PPVPs) using enhanced vitreous imaging of spectral domain optical coherence tomography.

Methods: Fifty-two highly myopic eyes with PPVPs of 36 patients were included in this study. All subjects underwent enhanced vitreous imaging optical coherence tomography. The size of PPVPs was measured, and the frequency of imaging features was recorded.

Results: Nine imaging features of the vitreous in highly myopic eyes with PPVPs were found. The average age of subjects was 38.1 ± 10.8 years. The mean height of PPVPs was 1,177 ± 704 μm, and the mean width was 7,440 ± 755 μm. Hyperreflective line and the interlayer were observed in 30 (57.7%) eyes. Hyperreflective dots were found in 37 (71.2%) eyes. More central vitreous space was more frequently detected in younger patients. Prevascular vitreous fissure was detected in 7 (13.5%) eyes. W-shaped cavity, identified as an empty space with a smooth W-shaped edge, was demonstrated to be the fusion of Cloquet's canal and the extension of PPVPs. Perpendicular hyperreflective parallel strands were detected in 3 (5.8%) eyes. Hyperreflective network was observed in 10 (19.2%) eyes. Hyperreflective parapapillary tubercle was found in 7 (13.5%) eyes.

Conclusion: Nine imaging features of the vitreous in highly myopic eyes with PPVPs were visualized by enhanced vitreous imaging optical coherence tomography.

Nine imaging features of the vitreous in highly myopic eyes with posterior precortical vitreous pockets were visualized using enhanced vitreous imaging of spectral domain optical coherence tomography. The authors' observations may have implications in the pathogenesis of early vitreous change in high myopia.

*Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), School of Medicine, Shanghai Jiao Tong University, Shanghai, China;

Shanghai Key Laboratory of Fundus Diseases, Shanghai, China; and

Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.

Reprint requests: Fenghua Wang, MD, Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), School of Medicine, Shanghai Jiao Tong University, 100 Haining Road, Shanghai, China, 200080; e-mail: shretina@sjtu.edu.cn

Supported by the National Science Fund for Distinguished Young Scholars (81425006), Translational Medicine Innovation Fund of Shanghai Jiao Tong University School of Medicine (15ZH4005), Science and Technology Commission of Shanghai Municipality (16dz2251500), Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support (20152229), Science and Technology Commission of Shanghai Municipality (16411952900), and the National Natural Science Foundation of China (81470640).

None of the authors has any financial/conflicting interests to disclose.

X. Wang and M. Shen contributed equally to this study and share first authorship.

© 2018 by Ophthalmic Communications Society, Inc.