To investigate the angiographic findings assessed using fluorescein angiography (FA) and their prognostic values of idiopathic epiretinal membrane (iERM).
Seventy-three eyes of iERM that had been followed-up for 6 months after surgical treatment were included. Mid-phase FA images were obtained at baseline. Structural changes, including central subfield macular thickness (CSMT), intraretinal cystic lesion, and ectopic inner retinal layer (EIRL) on the fovea, were assessed using optical coherence tomography (OCT). The main outcome measures were microvascular leakage (ML) and its association with OCT findings and best-corrected visual acuity (BCVA).
Of a total of 73 eyes, 37 showed ML and had worse BCVA (P = 0.040), greater CSMT (P = 0.028), and more EIRL (P < 0.001) than those without ML at baseline. ML was associated with worse postoperative BCVA (P < 0.001) and EIRLs (P < 0.001, P = 0.034) at baseline and 6 months. The baseline factors associated with postoperative BCVA of ≥ 20/25 were better BCVA (P = 0.027) and the absence of ML (P < 0.001).
Half of the iERM eyes showed that ML was associated with inner retinal deformity and poor visual recovery. FA helped predict visual prognosis after iERM surgery.