Original StudyFINGERPRINT SIGN OF THE HENLE FIBER LAYERGriffin, Shane M. BA*; McDonald, H. Richard MD†,‡; Johnson, Robert N. MD†,‡; Jumper, J. Michael MD†,‡; Fu, Arthur D. MD†,‡; Cunningham, Emmett T. Jr MD, PhD, MPH†,‡,§,¶; Kiang, Lee MD, PhD*; Ng, Caleb C. MD†,‡; Lujan, Brandon J. MD*,†Author Information *Casey Eye Institute, Oregon Health & Science University, Portland, Oregon; †West Coast Retina Medical Group, San Francisco, California; ‡Department of Ophthalmology, California Pacific Medical Center, San Francisco, California; §Department of Ophthalmology, Stanford University School of Medicine, Stanford, California; and ¶The Francis I Proctor Foundation, UCSF School of Medicine, San Francisco, California Reprint requests: Brandon J. Lujan, MD, Casey Eye Institute, 515 SW Campus Dr, Portland, OR 97239; e-mail: [email protected] Supported by grant P30 EY010572 from the National Institutes of Health (Bethesda, MD) and by unrestricted departmental funding from the Research to Prevent Blindness (New York, NY). None of the authors has any financial/conflicting interests to disclose. Retina: February 2021 - Volume 41 - Issue 2 - p 381-386 doi: 10.1097/IAE.0000000000002875 Buy Metrics AbstractIn Brief Purpose: To describe the appearance of concentric, fingerprint-like waves within the Henle fiber layer (HFL) using en face optical coherence tomography in patients with tractional pathologies of the retina. Methods: Retrospective analysis of six eyes of six patients imaged by optical coherence tomography with volumetric slabs positioned at the level of the HFL. Results: Optical coherence tomography data from six patients with tractional vitreoretinal pathology were reviewed. Concentric, fingerprint-like microwaves were visualized through en face optical coherence tomography in all six study eyes at the level of the HFL. This finding resembled the finding of HFL waves previously noted histopathologically from force exerted on this layer. Conclusion: In retinal pathologies in which specific physical forces act on the retina, volumetric optical coherence tomography may permit visualization of en face concentric, fingerprint-like hyperreflective rings within the HFL. This “fingerprint sign” may represent a biomechanical consequence of traction on the retina and allow clinical decision making based on improved recognition of the existence of such traction. Concentric hyperreflective rings visualized by en face optical coherence tomography in patients with tractional pathologies of the retina may be caused by physical waves within the Henle fiber layer.