To develop a mathematical model of local blood flow in the choriocapillaris using an Ising model.
Much the same as actual choriocapillaris images in humans, the model of flow-related signal voids followed a power-law distribution. The slope and intercept both decreased with age, as is seen in human subjects.
This model is a working hypothesis, and as such can help predict system characteristics, evaluate conclusions drawn from studies, suggest new research questions, and provide a way of obtaining an estimate of behavior in which experimental data are not yet available. It may be possible to understand choriocapillaris blood flow in health and disease states by determining by observing deviations from an expected model.
A statistical mechanical model of choriocapillaris blood flow produces representations of choriocapillaris flow voids that follow the mathematical characteristics of those seen in images of human subjects.
Vitreous, Retina, Macula Consultants of New York, New York, New York.
Reprint requests: Richard F. Spaide, MD, Vitreous, Retina, Macula Consultants of New York, 460 Park Avenue, 5th Floor, New York, NY 10022; e-mail: email@example.com
Supported in part by the Macula Foundation, New York, NY.
The author receives consulting fees from Topcon Medical Systems.
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