Background: Contrast sensitivity
(CS) is a valuable measure of visual function in patients with age-related macular degeneration
(AMD). The authors aimed to compare a novel computer-based test (the Spaeth/Richman Contrast Sensitivity test
) with Pelli–Robson
test for evaluating CS in patients with AMD.
In this prospective cross-sectional study, CS was evaluated in patients with various stages of AMD and healthy controls using Spaeth/Richman Contrast Sensitivity test
test. Spaeth/Richman Contrast Sensitivity test
determined CS scores for 5 areas of vision for each eye (central, superonasal, superotemporal, inferonasal, and inferotemporal) and the total score. Test scores between the two methods were compared using mixed-effects linear regression. Spearman's rank correlation coefficient was used to determine correlations. Test–retest reliability was determined using the intraclass correlation coefficient.
Of 35 participants with AMD (54 eyes) and 34 controls (66 eyes), 51% were female and 93% were of European descent. The mean Spaeth/Richman Contrast Sensitivity test
score for the central area and each of the 4 peripheral quadrants was significantly lower for patients with AMD versus controls (P
< 0.001 for all). The mean Pelli–Robson
score was also significantly lower in patients with AMD versus controls (P
< 0.001). The intraclass correlation coefficient for Spaeth/Richman Contrast Sensitivity test
total score and Pelli–Robson
score was 0.87 and 0.92, respectively.
Conclusion: Spaeth/Richman Contrast Sensitivity test
, a novel Internet-based method of testing CS, had significantly lower scores for patients with AMD compared with controls for central and peripheral vision. This test is a valuable tool for assessing CS in AMD.