CHOROIDAL THICKNESS IN EYES WITH TILTED DISK SYNDROMEUeno, Chikako MD; Gomi, Fumi MD; Ikuno, Yasushi MD; Nakai, Kei MD; Sawa, Miki MD; Nishida, Kohji MDRETINA: March 2014 - Volume 34 - Issue 3 - p 497–503 doi: 10.1097/IAE.0b013e3182a1ca40 Original Study Abstract In Brief Author Information Purpose: To investigate the choroidal thickness in eyes with tilted disk syndrome within/without posterior staphyloma. Methods: Twenty-one eyes examined in 16 patients with tilted disk syndrome were included. The thicknesses of the choriocapillaris, the medium-to-large choroidal vessels, and total choroids found 1 mm and 3 mm superior and inferior to the fovea and in the area with the thinnest choroid were measured using enhanced-depth imaging optical coherence tomography or high-penetration optical coherence tomography. The results were compared with the findings on indocyanine green angiography. Results: The mean thicknesses of total choroid found 3 mm and 1 mm inferior (114.3 μm ± 77.8 μm, 145.0 μm ± 85.9 μm) to the fovea were significantly thinner than those found superior (174.5 μm ± 89.7 μm, 145.0 μm ± 85.9 μm) to it. The minimal choroidal thickness of 80.5 μm ± 67.1 μm was obtained at a mean 1.04 mm below the fovea at the upper edge of the posterior staphyloma. The thickness of the layer of choriocapillaris was not significantly different according to the regions but the layer of medium-to-large choroidal vessels found 3 mm and 1 mm inferior to the fovea was significantly thinner than that found superior to the fovea. The ratio of choriocapillaris to medium-to-large vessels found 1 mm superior also was significantly smaller than those found inferior. The diameter of medium-to-large choroidal vessels on ICGA was not significantly different in the areas although less number of vessels were seen around the area inferior to the fovea. Conclusion: In the eyes of patients with tilted disk syndrome, the choroid is thinnest at approximately 1 mm inferior to the fovea at the upper edge of the posterior staphyloma rather than at the bottom of the posterior staphyloma. Thinning of the layer of medium-to-large choroidal vessels seems to be associated with the thinning of choroid thickness. In the eyes of patients with tilted disk syndrome, the choroid is thinnest at approximately 1 mm inferior to the fovea at the upper edge of the posterior staphyloma rather than at the bottom of the posterior staphyloma. The reduction of choroidal thickness is mainly because of the thinning of the layer of medium-to-large vessels rather than choriocapillaris. Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan. Reprint requests: Fumi Gomi, MD, Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan; e-mail: email@example.com None of the authors have any financial/conflicting interests to disclose. © 2014 by Ophthalmic Communications Society, Inc.