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Dugel, Pravin U. MD*; Zhou, Jianbo PhD; Abulon, Dina Joy K. MS; Buboltz, David C. MBA

doi: 10.1097/IAE.0b013e3182456f4d
Original Study

Purpose: To evaluate the influence of different vitrectomy probe gauge sizes and their fluidics, under various vacuum settings, on tissue attraction.

Methods: An apparatus was designed to model the retinal membrane during vitrectomy. A cantilever beam was constructed from a wire (diameter, 0.076 mm) with a latex strip (simulating ocular membranes) attached at a right angle to its tip. The beam was clamped vertically in a container of balanced salt solution. The port of the vitrectomy probe (20 gauge, 23 gauge, and enhanced 25 gauge) was aligned with the membrane. With the cutter off, the vacuum was increased until the membrane was attracted into the port. The aspiration flow rate was measured with a noninvasive flow meter. Attraction distance, vacuum pressure, and flow rate were recorded.

Results: For any given distance, the 20-gauge probe needed the lowest amount of vacuum and the highest aspiration flow, while the enhanced 25-gauge and 23-gauge probes needed larger vacuum and smaller aspiration flow rates to attract the membrane into the port.

Conclusion: The sphere of influence on surrounding tissue was greatest with large-gauge vitrectomy probes. This laboratory model indicated that small-gauge probes could be used to target specific tissues while minimizing the effects on adjacent tissue structures.

A laboratory model indicated that specific membranes and tissues could be targeted during vitreoretinal tissue dissection by selection of smaller-gauge probes.

*Retinal Consultants of AZ, Ltd, Phoenix, Arizona

Global Medical Affairs, Alcon Research, Ltd.; Irvine, California.

Reprint requests: David C. Buboltz, MBA, Alcon Research, Ltd, 6201 South Freeway, Fort Worth, TX 76134; e-mail:

Supported by Alcon Research, Ltd; Irvine, CA, which also provided medical writing support for this manuscript.

P. U. Dugel is a consultant for Alcon. D. C. Buboltz, D. J. K. Abulon, and J. Zhou were employees of Alcon Research during the conduct of the study.

© The Ophthalmic Communications Society, Inc.