Eleven patients, 40 to 71 years old, had a choroidal vasculopathy that led to hemorrhagic and exudative macular degeneration. The patients had peculiar polypoidal, subretinal, vascular lesions associated with serous and hemorrhagic detachments of the retinal pigment epithelium. This macular disorder, which we have named idiopathic polypoidal choroidal vasculopathy (IPCV), appears to represent a distinct entity that differs clinically and demograph-ically from age-related macular degeneration (AMD) and other macular diseases associated with subretinal neovascularization. Recognition of this condition is important because it may have specific risk factors, natural course, and management considerations that differ from those of age-related macular degeneration.
LuEsther T. Mertz Retinal Research Lab and The Macula Foundation, Manhattan Eye, Ear and Throat Hospital, New York, NY.
Reprint requests: Dr. Lawrence A. Yannuzzi, Manhattan Eye, Ear and Throat Hospital, 210 E. 64th St., New York, NY 10021.