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Chen, San-Ni MD*†; Hwang, Jiunn-Feng MD*†; Chen, Yan-Ting MD*

doi: 10.1097/IAE.0b013e3181f2a15c
Original Study

Purpose: To evaluate the structural features of central retinal artery occlusion by means of optical coherence tomography.

Methods: Eleven consecutive patients with acute central retinal artery occlusion and at least 3-month follow-up were enrolled prospectively in this study. The main outcome measures included best-corrected visual acuity, foveal thickness (FT), and total macular volume by optical coherence tomography.

Results: Five male and six female patients with central retinal artery occlusion were examined. The mean age was 71.2 ± 8.7 years (range, 59-83 years). Mean FT and total macular volume were 195 ± 26 μm and 6.41 ± 0.33 mm3, respectively, in normal fellow eyes, increased to 299 ± 76 μm and 7.90 ± 0.93 mm3, respectively, at initial examination and declined to 167 ± 30 μm and 4.85 ± 0.68 mm3, respectively, at 3-month follow-up. Mean reduction in FT was 181 ± 61 μm (range, 120-270 μm) in eyes with poor visual outcome and 43 ± 25 μm (range, 15-74 μm) in eyes with fair visual outcome. Statistical analysis revealed that the relationships among visual prognosis and initial FT and initial total macular volume were not significant.

Conclusion: Optical coherence tomography provides special information about central retinal artery occlusion. There were marked and variable changes in FT and total macular volume. Limited reduction in macular thickness might indicate a fair visual outcome.

Changes in macular thickness in eyes with central retinal artery occlusion were evaluated by optical coherence tomography. Mean foveal thickness increased to 299 ± 76 μm at initial examination and declined to 167 ± 30 μm at 3-month follow-up. Eye with fair visual outcome poses limited reduction in macular thickness.

From the *Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan; and †School of Medicine, Chung Shan Medical University, Taichung, Taiwan.

The authors indicate no financial support or conflict of interest.

The study protocol followed the tenets of the Declaration of Helsinki. Informed consent was obtained from each subject before enrollment in the study. The designs and procedures of this study were approved by the Institutional Review Board of the Changhua Christian Hospital.

Reprint requests: Jiunn-Feng Hwang, MD, Department of Ophthalmology, Changhua Christian Hospital, 135 Nan-Siao Street, Changhua 500, Taiwan: e-mail:

© The Ophthalmic Communications Society, Inc.