Original ArticlesLONG-TERM JUXTAFOVEAL RETINAL TELANGIECTASIAWATZKE, ROBERT C. MD*; KLEIN, MICHAEL L. MD*; FOLK, JAMES C. MD†; FARMER, SAMUEL G. MD‡; MUNSEN, RICHARD S. MD§; CHAMPFER, ROBERT J. MD¶; SLETTEN, K R. MD†Author Information From the *Casey Eye Institute, Oregon Health & Science University, Portland, Oregon; the †Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City, Iowa; ‡2450 12th Street SE, Salem, Oregon; §1221 Madison Street, Seattle, Washington; and ¶1550 Oak Street, Eugene, Oregon. Reprint requests: Robert C. Watzke, MD, Casey Eye Institute, Oregon Health & Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239-4197; e-mail: [email protected] Supported in part by an unrestricted grant to Casey Eye Institute from Research to Prevent Blindness, New York, NY. The authors have no financial or proprietary interest in any product discussed in this article. Retina: September 2005 - Volume 25 - Issue 6 - p 727-735 Buy AbstractIn Brief Purpose: To determine the long-term natural history of idiopathic juxtafoveal telangiectasia (IJRT). Methods: Record review in 2 university-based and 2 private vitreoretinal practices sought patients with IJRT documented by color photographs and fluorescein angiograms (FAs) during the period January 1, 1980, to December 31, 1993. Patients then had repeated examinations and FAs. Results: Twenty patients with IJRT in 32 eyes had follow-up examinations. Fifteen patients had color photographs and FAs, and one had color photographs alone. Follow-up varied from 10 years to 21 years (average, 15 years). Six eyes were treated by laser photocoagulation at onset. Twenty-four of the 26 untreated eyes lost vision as measured by Snellen testing. Visual loss and morphologic progression depended on IJRT type. Six of 8 untreated eyes with type IA IJRT lost vision by ≥3 lines (Snellen), 4 to 20/70 or worse. Vision loss was caused by progressive telangiectatic changes and intraretinal edema. Fifteen of 20 initially untreated eyes with type IIA IJRT developed either central retinal pigment epithelium membranes or subretinal neovascularization with loss of vision to 20/80 or less. Conclusion: IJRT prognosis depends on type and clinical features. Long-term prognosis for central vision is poor. Ten-year to 20-year follow-up of 20 patients (32 eyes) with juxtafoveal retinal telangiectasia (JRT) concluded that visual prognosis is poor and morphologic progression varies depending on JRT type. Eyes with Gass type IA JRT developed extensive intraretinal edema; eyes with Gass type IIA IJRT developed either pigmented foveal scars or progressive retinal neovascularization. © The Ophthalmic Communications Society, Inc.