FOVEAL SPOTA Report of Thirteen PatientsDOUGLAS, RAYMOND S. MD, PhD*; DUNCAN, JACQUE MD†; BRUCKER, ALLISON BS*; PRENNER, JONATHAN L. MD*; BRUCKER, ALEXANDER J. MD* Author Information *From the Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania; and the †Department of Ophthalmology, University of California at San Francisco, San Francisco, California. This paper was presented at the Macula Society Annual Meeting; Scottsdale, Arizona; February 2, 2001. The authors have no proprietary interest in the work presented. Reprint requests: Alexander J. Brucker, MD, Scheie Eye Institute, 51 North 39th Street, Philadelphia, PA 19103. Retina: June 2003 - Volume 23 - Issue 3 - p 348-353 Buy Abstract Purpose: To describe the natural history of a series of patients with a small foveal or juxtafoveal red lesion. Methods: Retrospective chart review of 13 patients with a small foveal or juxtafoveal red spot. Long-term follow-up examination was obtained in seven patients. Results: Thirteen patients with a mean age of 34.6 years are reported. Initial visual complaints ranged from no complaints to mild blurring and central distortion of vision. None of the patients had a history of sun gazing or known macular disease. Eleven of the 13 patients had best-corrected visual acuities in the involved eye that were better than 20/30. The lesions were bilateral in five patients and unilateral in eight. When performed, optical coherence tomography and fluorescein angiography were unremarkable. Follow-up was obtained in seven patients (mean, 58 months), and visual acuity remained stable in all affected eyes. In all patients, the lesions remained stable without expansion or alteration of the foveal appearance over the course of follow-up. Conclusions: This report identifies a foveal or juxtafoveal, irregular, apparently intraretinal, red lesion of unclear cause. Long-term follow-up of these patients has demonstrated stable visual acuity and lesion appearance. © The Ophthalmic Communications Society, Inc.