“ON” RESPONSE DYSFUNCTION IN MULTIFOCAL POSTERIOR PIGMENT EPITHELIOPATHYIMAIZUMI, MASAMOTO MD, PhD; MATSUMOTO, CELSO SOITI MD, PhD; KIMOTO, KEN-ICHI MD; FURUSHIMA, MASATOSHI MD, PhD; NAKATSUKA, KAZUO MD, PhDRetina: February 2002 - Volume 22 - Issue 1 - p 33-36 Articles Buy Abstract Author InformationAuthors Purpose To determine the electroretinographic properties of one patient with multifocal posterior pigment epitheliopathy. Methods Rod and cone electroretinograms (ERGs) and photopic ERGs elicited by long-duration stimuli were studied in a patient with multifocal posterior pigment epitheliopathy. Results The amplitudes of both the rod and cone ERGs were significantly reduced. Photopic ERGs elicited by long-duration stimuli demonstrated that the b-wave (“on” response) was abolished but the d-wave (“off” response) was reduced by only amplitude. Conclusion The ERG findings in multifocal posterior pigment epitheliopathy indicate that there is dysfunction not only of the photoreceptors but also in the signal transmission specific for the “on” pathway. From the Department of Ophthalmology, Oita Medical University, Hasama-machi, Oita-ken, Japan. Reprint requests: Masamoto Imaizumi, MD, PhD, Department of Ophthalmology, Oita Prefectural Hospital, 476 Bunyo, Oita 870-855, Japan. The authors have no proprietary interest in this study. © The Ophthalmic Communications Society, Inc.