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Examining Factors Related to Health-Related Quality of Life in People With Parkinson’s Disease

Kwok, JoJo Yan Yan, PhD candidate, MPH, BN(Hons), RN1; Auyeung, Man, MBChB, FHKCP, FHKAM(Med), MHKCP, MRCO(UK)2; Chan, Helen Yue Lai, PhD, BSN(Hons), RN1

doi: 10.1097/rnj.0000000000000179
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Purpose Parkinson’s disease (PD) results in a range of dysfunctions and disabilities as it progresses to later stages. All these not only affect a patient’s physical well-being but also emotional, social, and spiritual well-being. To tailor interventions that can address these concerns, this study aimed to examine the impacts of PD on their health-related quality of life (HRQOL).

Design A cross-sectional study with 123 PD patients.

Methods Measures included the following: Hospital Anxiety and Depression Scale, Unified PD Rating Scale–Motor Examination, Hoehn and Yahr Stage, PD Questionnaire-8. Associating factors of HRQOL was examined using stepwise linear regression.

Findings Psychological distress and functional impairment are significantly associated with the HRQOL of the PD population. Psychological distress is associated most to the variance of HRQOL (42.4%).

Conclusion Considering that PD is chronic, rehabilitation programs should be applied to address not just functional but also psychosocial needs of PD patients.

Clinical Relevance Early recognition and management of psychological distress in PD patients is indispensable to promote their HRQOL.

1 The Nethersole School of Nursing, The Chinese University of Hong Kong, Shatin, Hong Kong SAR

2 Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong SAR

Correspondence: JoJo Yan Yan Kwok The Nethersole School of Nursing, The Chinese University of Hong Kong, Shatin, Hong Kong SAR. E-mail:;

The abstract was presented at the 21st International Congress of Parkinson’s Disease and Movement Disorders, Vancouver, BC (June 4–8, 2017), and has been awarded the 2017 International Congress Travel Grants Award.

© 2019 Association of Rehabilitation Nurses.
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