FeatureAdherence to Therapy: Using an Evidence-Based ProtocolMoore, Linda A. EdD APRN BC ANP/GNP MSCN1; Kaufman, Michael D. MD2; Algozzine, Robert PhD3; Irish, Nikki MSN APRN BC ANP4; Martin, Mary LPN5; Posey, Carol Rosser MSN APRN ANP6Author Information 1 Linda A. Moore, EdD APRN BC ANP/GNP MSCN, is an associate professor and nurse practitioner at UNC Charlotte, College of Health and Human Services & the Multiple Sclerosis Center, Carolinas HealthCare System in Charlotte, NC. 2 Michael D. Kaufman, MD, is a medical director in the MS Center, Carolina Healthcare System, Charlotte, NC. 3 Robert Algozzine, PhD, is a professor at UNC Charlotte School of Education. 4 Nikki Irish, MSN APRN BC ANP, is a nurse practitioner and professional educator. 5 Mary Martin is an LPN at Raleigh University. 6 Carol Rosser Posey, MSN APRN ANP, is a nurse practitioner at Advanced Occupational Health Services. Correspondence to [email protected]. Rehabilitation Nursing Journal: November 2007 - Volume 32 - Issue 6 - p 227-232 doi: 10.1002/j.2048-7940.2007.tb00179.x Buy Metrics Abstract The number of patients receiving injectable medications has increased significantly during the past few years. Today, patients with hepatitis, rheumatoid arthritis, and multiple sclerosis are added to the list of those, namely diabetics, who have been instructed in self-administration of injectable medications. Currently, some of these medications create significant skin site reactions, and patients tend to discontinue the medications without informing the healthcare provider. Determining the problem and developing a research study that provides evidence to demonstrate methods to help patients adhere to agreed-upon treatment modalities can be accomplished within the clinical practice setting. This study provided a method to decrease skin reactions with interferon 1-b injections for multiple sclerosis patients and has been continued as a method with other like medications. © 2007 Association of Rehabilitation Nurses.