Dr Kledzik is Assistant Professor of Clinical Psychiatry and Dr Thorne is Assistant Professor of Clinical Psychology in Clinical Psychiatry, Riley Hospital for Children, Indiana University School of Medicine, 705 Riley Hospital Dr Ste 4300, Indianapolis, IN 46202.

All faculty and staff in a position to control the content of this CME activity and their spouses/life partners (if any) have disclosed that they have no financial relationships with, or financial interests in, any commercial companies pertaining to this educational activity.

The authors have disclosed that the use of ramelteon for treatment of anxiety and the use of agomelatine for treatment of depression as discussed in this article has not been approved by the US Food and Drug Administration.