Articles: PDF OnlyClub Drugs, Part II: GHBTeter, Christian J. PharmD, BCPP Author Information CME article by Christian J. Teter, PharmD, BCPP, Post-Doctoral Fellow (NIDA), College of Pharmacy & Substance Abuse Research Center, University of Michigan The author has disclosed that he has no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity. The author has disclosed that the use of gamma hydroxybutyric acid has not been approved by the U.S. Food and Drug Administration for use as an anesthetic or for the treatment of alcohol abuse or opium withdrawal. This article is adapted from Teter CJ, Guthrie SK. A comprehensive review of MDMA and GHB: Two common club drugs. Pharmacotherapy 2001;21:1486–1513. Reprinted with permission. International Drug Therapy Newsletter: August 2003 - Volume 38 - Issue 8 - p 57-64 Buy Abstract Learning Objectives: After reading this article, the practitioner should be able to: Distinguish between the therapeutic and illicit uses for gamma hydroxybutyric acid (GHB) in the United States. State the pharmacokinetic parameters of GHB. Describe GHB's receptor biochemistry. Recall the signs and symptoms of acute reactions associated with GHB ingestion and explain possible treatment options for acute GHB intoxication. © 2003 Lippincott Williams & Wilkins, Inc.