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September/October 2021 - Volume 41 - Issue 5

  • Anthony J. Rothschild, MD
  • 0271-0749
  • 1533-712X
  • 6 issues / year
  • Psychiatry 69/155; Pharmacy and Pharmacology 133/270
  • 3.153

Photo -AJ Rothschild, MD in front of medical school.jpg

Welcome to the September-October 2021 issue of the Journal of Clinical Psychopharmacology.  There are many interesting and thought-provoking articles in this issue. I would like to highlight a few of them. This month’s issue features a Guest Editorial by Richard Shader, our Founding Editor-in-Chief Emeritus, on “The Placenta and Psychiatry?”​ The Editorial is accompanied by a podcast with Dr. Julia Ann Koretski, our Digital Editor, who adds her own insights and experiences on the topic. Dr. Christiaan H. Vinkers and colleagues have written an interesting Commentary entitled, “Antidepressant Discontinuation:  In Need of Scientific Evidence,” discussing important questions such as who can discontinue antidepressants, when to discontinue antidepressants, and how to discontinue antidepressants. Dr. Carla Canuso and colleagues present post hoc analyses of pooled data from the recently completed ASPIRE trials, entitled "Esketamine Nasal Spray for the Rapid Reduction of Depressive Symptoms in Major Depressive Disorder With Acute Suicidal Ideation or Behavior."  The paper is accompanied by a podcast with Drs. Carla Canuso and Dong-Jing Fu. In a Brief Report, Dr. Michael Banov and colleagues present data on 10 patients who maintained the antidepressant response to intravenous racemic ketamine when switched to intranasal esketamine. Finally, in a Letter to the Editor​, Dr. Sherwood Brown discusses a program at the University of Texas Southwestern Medical Center entitled “Developing a Sustained and Productive Clinical Research Seminar”.  And as you will see, there are many other interesting Original Contributions, Brief Reports, and Letters to the Editor in this issue!  

Anthony J. Rothschild, MD
Editor-in-Chief

Current Issue Highlights




Esketamine Nasal Spray for the Rapid Reduction of Depressive Symptoms in Major Depressive Disorder With Acute Suicidal Ideation or Behavior

Canuso, Carla M.; Ionescu, Dawn F.; Li, Xiang; More

Journal of Clinical Psychopharmacology. 41(5):516-524, September/October 2021.




Effectiveness of Intramuscular Chlorpromazine for Rapid Treatment of Psychomotor Agitation: A Naturalistic, Retrospective, and Observational Study

Cuomo, Alessandro; Chioccioli, Marco; Cattaneo, Carlo Ignazio; More

Journal of Clinical Psychopharmacology. 41(5):613-614, September/October 2021.


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