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Original Contributions

Influence of Dose, Cigarette Smoking, Age, Sex, and Metabolic Activity on Plasma Clozapine Concentrations: A Predictive Model and Nomograms to Aid Clozapine Dose Adjustment and to Assess Compliance in Individual Patients

Rostami-Hodjegan, Amin PhD*; Amin, Ajmal M. MSc†‡; Spencer, Edgar P. PhD; Lennard, Martin S. PhD*; Tucker, Geoffrey T. PhD*; Flanagan, Robert J. PhD

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Journal of Clinical Psychopharmacology: February 2004 - Volume 24 - Issue 1 - p 70-78
doi: 10.1097/
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© 2004 Lippincott Williams & Wilkins, Inc.